2nd Edition

Handbook of Dynein (Second Edition)

Edited By Keiko Hirose Copyright 2019
436 Pages 34 Color & 48 B/W Illustrations
by Jenny Stanford Publishing

436 Pages 34 Color & 48 B/W Illustrations
by Jenny Stanford Publishing

Dyneins are molecular motors that are involved in various cellular processes, such as cilia and flagella motility, vesicular transport, and mitosis. Since the first edition of this book was published in 2012, there has been a significant breakthrough: the crystal structures of the motor domains of cytoplasmic dynein have been solved and the previously unknown details of this huge and complex... Read more

Dyneins: Ancient Protein Complexes Gradually Reveal Their Secrets. L Amos & K Hirose

Structural and Functional Analysis of the Dynein Motor Domain. T Shima & T Kon

Electron Microscopy Studies of Dynein: From Subdomains to Microtubule-Bound Assemblies. A Roberts et al.

Subunit Architecture of the Cytoplasmic Dynein Tail. M Ichikawa et al.

Measuring the Motile Properties of Single Dynein Molecules. H Higuchi & C Shingyoji

Mechanics of Dynein Motility. A Yildiz

Interactions of Multiple Dynein Motors Studied Using DNA Scaffolding. N Derr

Cytoplasmic Dynein Force Regulation in Vitro and in Vivo. C Wynne & R Vallee

Dynein in Endosome and Phagosome Maturation A Rai, D Pathak & R Mallik

Dynein in Intraflagellar Transport. K Lechtreck

Diversity of Chlamydomonas Axonemal Dyneins. T Yagi & R Kamiya

Motility of Axonemal Dyneins. M Shiraga et al.

Axonemal Dyneins in Cilia and Flagella. T Ishikawa

Regulatory Mechanism of Axonemal Dynein. K Inaba

Biography

Keiko Hirose is a researcher with more than 30 years’ experience in structural and functional studies of motor proteins. She has a PhD from the University of Tokyo and was a postdoctoral fellow at the University of Pennsylvania and at the MRC Laboratory of Molecular Biology, Cambridge, UK. She is especially interested in how molecular motor proteins, such as dynein, move. Dr. Hirose has been working at the National Institute of Advanced Industrial Science and Technology, Japan, since 1997.

Given the recent explosion of interest in dynein, this book gives a timely review of both historical and current developments in the field. It is an extensive compendium compiled by leading dynein researchers and an excellent resource for young and experienced scientists alike!

Prof. Joe Howard - Max Planck Institute of Molecular Cell Biology and Genetics, Germany

Handbook of Dynein, edited by the eminent electron microscopists Keiko Hirose and Linda Amos and contributed to by many international leading scientists in the field, is an excellent introduction to cutting-edge dynein research, including such aspects as biochemistry, molecular biology, biophysics, structural biology, and molecular genetics. It introduces not only the mechanisms of how cilia and flagella move and how the intracellular transport is performed by dyneins but also the pathogenesis of diseases related to the dynein motor complex. Thus, it will be a really fine handbook for students and researchers in the broad areas of life sciences.

Prof. Nobutaka Hirokawa - University of Tokyo, Japan