Handbook of Dystonia: 2nd Edition (Hardback) book cover

Handbook of Dystonia

2nd Edition

Edited by Mark A. Stacy

CRC Press

440 pages | 19 Color Illus.

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Hardback: 9781841848518
pub: 2012-05-28
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As many as 250,000 people in the United States have dystonia, making it the third most common movement disorder following essential tremor and Parkinson's disease.

Authoritative and reader-friendly, Handbook of Dystonia, Second Edition provides a wide-ranging overview of the latest research and developments regarding the pathogenesis, evaluation, and management of the disease. The book offers detailed coverage of every available treatment option for dystonia and includes four categorized sections on medical management, botulinum toxin injections, phenol and neurolytic therapy, and surgical intervention.

The book reviews the genetic factors of dystonia and supplies in-depth coverage of the neuroanatomy, neurophysiology, and neuropathology of the disease. It covers secondary causes of dystonia, including drug-induced and psychogenic presentations. It also examines non-motor symptoms relating to movement disorders and analyzes innovative approaches for treatment including deep brain stimulation.

New to the Second Edition:

  • Four new chapters dedicated to the discussion of individual botulinum toxins recently approved to treat dystonia: Botox, Myobloc, Disport, and Xeomin
  • Dystonic symptoms associated with Parkinson’s disorders
  • The use of Transcranial Magnetic Stimulation (TMS) as a treatment option for dystonia
  • Spasticity and its pathogenesis, evaluation, and treatment with toxins, other injectables and surgical therapies

Summarizing what is known about the disorder, the book dramatically improves the recognition and understanding of this debilitating disease.

Table of Contents


Introduction to Dystonia

Joohi Shahed; Joseph Jankovic

Epidemiology Dystonia

Giovanni Defazio

Genetic Evaluation in Hereditary Dystonia

Christine Klein; Laurie J. Ozelius

Functional Anatomy of the Basal Ganglia

Jonathan W. Mink

Physiology of Primary Dystonia

Holly A. Shill; Mark Hallett

Pathology of the Dystonias

Ruth H. Walker; Kevin StP. McNaught; Daniel Perl

Neuroimaging in Dystonia

A. R. Troiano; A. J. Stoessl


Primary Generalized Dystonia

Johan Samanta

Cranial Dystonia

Pankaj Satija; William G. Ondo

Cervical Dystonia

Khashayar Dashtipour; Mark Lew

Limb Dystonia

Barbara I. Karp

Spasmodic Dysphonia

Tanya K. Meyer; Andrew Blitzer

Embouchure and Other Task-Specific Musician’s Dystonias

Steven E. Lo; Steven J. Frucht

Sports-Related Task-Specific Dystonia: The Yips

Charles H. Adler

Dopa-Responsive Dystonia

Masaya Segawa; Yoshiko Nomura; Nobuyoshi Nishiyama

Rapid Onset Dystonia-Parkinson

Allison Brashear

Secondary Dystonia

Arif Dalvi; Kelly E. Lyons; Rajesh Pahwa

Dystonic Symptoms Associated with Parkinsonian Disorder

Eduardo Tolosa

Drug-Induced Dystonia

Francisco Cardoso

Psychogenic Dystonia

Anette Schrag; Anthony E. Lang

Nonmotor Symptoms in Dystonia

Stewart A. Factor; Daniel Huddleston; Felicia C. Goldstein; Lynn Marie Trott


Volker Dietz


Medical Therapy for Dystonia

Roongroj Bhidayasiri; Daniel Tarsy

Anatomic Principles for Botulinum Toxin Injection

Richard L. Barbano

Botulinum Toxin: From Molecule to Clinic

Nicole Calakos

Botulinum Toxins in the Treatment of Dystonia

Mark A. Stacy; Patrick Hickey

Botox onabotulinumtoxinA

David Charles; Chandler Gill

Myobloc rimabotulinumtoxinB

Christina Sampaio

Dysport abobotulinumtoxinA

Werner Poewe; Sascha Hering

Xeomin incobotulinumtoxinA

Dirk Dressler

Peripheral neurolysis in the treatment if dystonia

Alberto Esquenazi

Selective Denervation in Cervical Dystonia

Carlos A. Arce

Repetitive transcranial Magnetic Stimulation in the Treatment for Dystonia

Angelo Antonini; Francesca Morgante

Brain Surgery for Dystonia

Camilla Kilbane; William J. Marks, Jr.

About the Editor

Mark A. Stacy, Duke University Medical Center, North Carolina, USA

Handbook of Dystonia, Second Edition, will again be edited by Mark A. Stacy, whose reputation in the industry as an expert in this movement disorder has only grown since he developed the very successful first edition. Dr. Stacy, now a professor of neurology at Duke University, has attracted a team of internationally-recognised movement disorder specialists to write the first edition of the book. These experts have returned to update their chapters, and new treatment specialists have been recruited to write the new botulinum toxin chapters.

About the Series

Neurological Disease and Therapy

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Neurology
MEDICAL / Psychiatry / General