In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery.
This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. The materials discussed include liposome-scaffold systems, elastic liposomes, targeted liposomes, solid lipid nanoparticles, lipoproteins, exosomes, porous inorganic nanomaterials, silica nanoparticles, and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.
Table of Contents
Liposome-Scaffold Systems for Drug Delivery
Elastic Liposomes for Drug Delivery
Nicole J. Bassous, Amit K. Roy, and Thomas J. Webster
Recent Advances with Targeted Liposomes for Drug Delivery
Josimar O. Eloy et al.
Liposomal Drug Delivery System and Its Clinically Available Products
Upendra Bulbake, Nagavendra Kommineni, and Wahid Khan
Solid Lipid Nanoparticles
Lipoproteins for Biomedical Applications: Medical Imaging and Drug Delivery
Pratap C. Naha et al.
Exosomes in Cancer Disease, Progression, and Drug Resistance
Taraka Sai Pavan Grandhi, Rajeshwar Nitiyanandan, and Kaushal Rege
Porous Inorganic Nanomaterials for Drug Delivery
Elshaimaa Sayed et al.
Silica Nanoparticles for Diagnosis, Imaging and Theranostics
Jessica Rosenholm and Tuomas Näreoja
Silica Nanoparticles for Drug Delivery
Marisa Adams and Brian G. Trewyn
Hyaluronan-Functionalized Inorganic Nanohybrids for Drug Delivery
Hongbin Zhang and Zhixiang Cai
Vladimir Torchilin is University Distinguished Professor of pharmaceutical sciences and the Director of the Center for Pharmaceutical Biotechnology and Nanomedicine at Northeastern University, USA. His research interests include drug delivery and targeting, nanomedicine, multifunctional and stimuli-sensitive pharmaceutical nanocarriers, biomedical polymers, experimental cancer therapy, cancer immunology, and novel imaging agents. He has published more than 450 original papers, more than 150 reviews and book chapters, 12 books, and holds more than 40 patents. Google Scholar gives more than 66,000 citations of his work with H-index of 114. Prof. Torchilin is editor-in-chief of Drug Delivery and Current Drug Discovery Technologies and is on the editorial boards of several leading journals in the field, including Journal of Controlled Release (review editor), Bioconjugate Chemistry, Advanced Drug Delivery Reviews, European Journal of Pharmaceutics and Biopharmaceutics, Journal of Drug Targeting, Molecular Pharmaceutics, and Journal of Biomedical Nanotechnology. He is also a Full Member of the European Academy of Sciences and Fellow of the American Institute of Medical and Biological Engineering, American Association of Pharmaceutical Scientists (AAPS), and the Controlled Release Society. He is a recipient of the 1982 Lenin Prize in Science and Technology (the highest scientific award in the former USSR), the 2005 Research Achievements in Pharmaceutics and Drug Delivery Award from the AAPS, the 2007 Research Achievements Award from the Pharmaceutical Sciences World Congress, the 2009 AAPS Journal Award, the 2009 International Journal of Nanomedicine Distinguished Scientist Award, the 2010 Controlled Release Society Founders Award, the 2012 Life Time Achievements Award from the Journal of Drug Targeting, the 2012 Alec Bangham Life Time Award, and the 2013 Blaise Pascal Medal for Biomedicine from the European Academy of Sciences.