Nanoindentation is ideal for the characterization of inhomogeneous biological materials. However, the use of nanoindentation techniques in biological systems is associated with some distinctively different techniques and challenges. The book presents the basic science of nanoindentation, including the background of contact mechanics underlying indentation technique and the instrumentation used to gather mechanical data. It provides perspectives that are optimized for biological applications, including discussions on hydrated materials and adaptations for low-stiffness materials. The book also covers the applications of nanoindentation technique in biological materials. Highlighting current challenges, it concludes with an insightful forecast of the future.
Table of Contents
Indentation and Adhesion at Small Length Scales, R.F. Cook
Instrumentation and Experimentation, K.J. Van Vliet
Mechanics of Adhesion, R.F. Cook
Mechanics of Indentation, M.L Oyen
Computational Modeling of Indentation, X. Chen
Nanoindentation of Bone, V.L. Ferguson & S.E. Olesiak
Nanoindentation of Tooth Tissues, L.-H. He & M.V. Swain
Nanoindentation of Soft Tissues and Other Biological Materials, D.M. Ebenstein
Cells and Membranes, K.-K. Liu & K.-T. Wan
Michelle L. Oyen is a Lecturer in Mechanics of Biological Materials in the Mechanics and Materials Division and the Engineering for the Life Sciences group in the Cambridge University Engineering Department. She holds a BS degree in Materials Science and Engineering and an MS Degree in Engineering Mechanics, both from Michigan State University, and a PhD degree in Biophysical Sciences and Medical Physics from the University of Minnesota. She joined Cambridge Engineering in 2006 following an appointment as Research Scientist at the University of Virginia Center for Applied Biomechanics. She is a member of the Materials Research Society and the ASME Bioengineering Division, a principal editor for the Journal of Materials Research, a moderator of iMechanica and a founding committee member for the new UK-based bioengineering society.
"Michelle Oyen has done a superb job compiling experts in the field of nanoindentation. This book spans a wide variety of topics ranging from the fundamental theory and instrumentation of nanoindentation to its application in biological materials including soft tissues, mineralized tissues, and cell structures. This book is an excellent resource for students and researchers alike."
—Professor Lisa Pruitt, University of California, Berkeley, USA