Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures, Volume I book cover
1st Edition

Handbook of Nuclear Medicine and Molecular Imaging for Physicists
Instrumentation and Imaging Procedures, Volume I

Edited By

Michael Ljungberg

  • Available for pre-order. Item will ship after September 1, 2021
ISBN 9781138593268
September 1, 2021 Forthcoming by CRC Press
496 Pages 379 B/W Illustrations

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Book Description

This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, and looking ahead to future prospects.

This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine.

  • The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine
  • Edited by a leader in the field, with contributions from a team of experienced medical physicists
  • Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

Table of Contents

1.  The History of Nuclear Medicine
Bo-Anders Jönsson

2.  Basics of Nuclear Physics
Gudrun Alm Carlsson and Michael Ljungberg

3.  Basics of Radiation Interaction in Matter
Michael Ljungberg

4.  Radionuclide Production
Hans Lundqvist

5.  Radiometry
Mats Isaksson

6.  Scintillation Detectors
Per Roos

7.  Semiconductor Detectors
Per Roos

8.  Gamma Spectroscopy
Christopher Rääf

9.  Properties of the Digital Image
Katarina Sjögreen Gleisner

10.  Digital Image Processing
Johan Gustafsson

11.  Machine-Learning
Karl Åström

12.  Image File Structures in Nuclear Medicine
Charles Herbst

13.  The Scintillation Camera 
Jonathan Gear

14.  Collimators for Gamma Ray Imaging
Roel van Holen

15.  Image Acquisition Protocols
Jonathan Gear

16.  Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging
Michael Ljungberg and Kjell Erlandssson

17.  Dedicated Tomographic Single Photon Systems
Chi Liu and Jing Wu

18.  Positron Emission Tomography (PET)
Stefaan Vandenberghe

19.  Dead Time Effects in Nuclear Medicine Imaging Studies
Carlos Uribe and Anna Celler

20.  Principles of Iterative Reconstruction for Emission Tomography
Andrew J. Reader

21.  Clinical Molecular PET/CT Hybrid Imaging
Dimitris Visvikis

22.  Clinical Molecular PET/MRI Hybrid Imaging
Bernard Sattler

23.  Quality Assurance of Nuclear Medicine Systems
John Dickson

24.  Calibration and Traceability
Brian E. Zimmerman

25.  Activity Quantification from Planar images
Katarina Sjögreen Gleisner

26.  Quantitation in Emission Tomography
Brian F. Hutton, Kjell Erlandsson and Kris Thielemans

27.  Multicenter studies: Hardware and Software Requirements
Terez Sera, Ronald Boellaard, Andres Kaalep and  Michael Ljungberg

28.  Pre-Clinical Molecular Imaging Systems
Magnus Dahlbom

29.  Monte Carlo simulations of Nuclear Medicine Imaging Systems
David Sarrut and Michael Ljungberg

30.  Beta and Alpha Particle Autoradiography
Anders Örbom, Brian W. Miller and Tom Bäck

31.  Principles behind Computed Tomography (CT)
Mikael Gunnarsson and Kristina Ydström

32.  Principles behind Magnetic Resonance Imaging (MRI)
Ronnie Wirestam


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Michael Ljungberg is a Professor at Medical Radiation Physics, Lund, Lund University, Sweden. He started his research in the Monte Carlo field in 1983 through a project involving a simulation of whole-body counters but later changed the focus to more general applications in nuclear medicine imaging and SPECT. As a parallel to his development of the Monte Carlo code SIMIND, he started working in 1985 with quantitative SPECT and problems related to attenuation and scatter. After obtaining his PhD in 1990, he received a research assistant position that allowed him to continue developing SIMIND for quantitative SPECT applications and establish successful collaborations with international research groups. At this time, the SIMIND program also became used world-wide. Dr. Ljungberg later became an associate professor in 1994 and he received, after a couple of years working clinically as a nuclear medicine medical physicist, a full professorship in the Science Faculty at Lund University in 2005. He became the Head of the Department of Medical Radiation Physics at Lund University in 2013 and a full professor in the Medical Faculty at Lund University in 2015.

Beside from the development of SIMIND to include also new camera system such as CZT detectors, his research includes an extensive project in oncological nuclear medicine, where he, with colleagues, develop dosimetry methods based on quantitative SPECT, Monte-Carlo absorbed dose calculations, and methods for accurate 3D dose planning for internal radionuclide therapy. During the recent years, his has been focused on implementing Monte-Carlo based image reconstruction in SIMIND. He is also involved in the undergraduate education of medical physicists and bio-medical engineers and are supervising MSC and PhD students. In 2012, Professor Ljungberg became a member of the European Association of Nuclear Medicines task group on Dosimetry and served there for six years. He has published over 100 original papers, 18 conference proceedings, 18 books and book chapters and 14 peer-reviewed review papers.