5th Edition
Handbook of Obesity - Volume 2 Clinical Applications
Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of “Precision Medicine”, and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%.
This volume is structured into 5 parts:
- Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and results for preventing obesity, health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment
- Part 2 deals with evaluation of overweight patients, approaches for classifying obesity and using this knowledge to evaluate patients, and addressing ethnic and racial considerations in evaluating patients with obesity
- Part 3 explains the impact of lifestyle in managing obesity, which include behavioural management, diet, dietary composition, and meal timing, and the effects of physical activity and exercise in weight loss and weight loss maintenance
- Part 4 is focused on medications in the management of obesity. This includes drug selection, various classes of drugs, combination of drugs affecting weight loss, effect of herbal agents on weight loss and treatment of obesity in pediatric populations, genetic diseases causing obesity and the role of drugs in treating the dyslipidemias
- Part 5 discusses bariatric surgery, its history, procedure and effects in details, and other surgical techniques including electric stimulation of the vagus nerve, gastric balloons, intestinal liners, and liposuction
Preface
About the Editors
Associate Editors
Contributors
Introduction to Volume 2
PART 1: PREVENTION AND ECONOMIC OUTCOMES OF OBESITY
1. Dietary Changes in Human Evolution: Implications for the Prevention of Obesity
Peter Andrews and Richard Johnson
2. Evolutionary Changes in Physical Activity, Diet, and Energy Expenditure: Implications for the Prevention of Obesity
Herman Pontzer
3. Prevention of Obesity in Adults
Suzanne Phelan
4. The Prevention of Obesity in Children and Adolescents
Tim Lobstein and Louise Baur
5. Re-engineering the Built Environment: Progress in Schools, Worksites, Neighborhoods, and Communities
Stephanie T. Broyles and Maura M. Kepper
6. The Economic Costs of Obesity
Adam Biener, John Cawley, and Chad Meyerhoefer
7. Cost-Effectiveness of Obesity Prevention and Treatment
Jaithri Ananthapavan, Marj Moodie, and Victoria Brown
8. Role of Government and Non-government Organizations in the Obesity Pandemic and Its Prevention
Simon Barquera, Mariel White, Gabriela Argumedo, Carolina Batis, and Juan Rivera-Dommarco
9. Role of Reimbursement in the Delivery of Treatment for Obesity in Adults and Children
Chika Vera Anekwe, Veronica R. Johnson, Matthew J. Townsend, and Fatima Cody Stanford
PART 2: EVALUATION OF THE PATIENTS WITH OVERWEIGHT OR OBESITY
10. Classification, Evaluation, and Staging of the Patient with Obesity
Robert F. Kushner and Amanda Velazquez
11. Indicators of Central Adiposity: A Critical Evaluation of Their Usefulness
Ian J. Neeland, Jean-Pierre Després, André C. Carpentier, and Paul Poirier
12. Genetic Obesity Syndromes
I. Sadaf Farooqi and Stephen O’Rahilly
13. Ethnic and Racial Considerations in the Evaluation of the Patient with Obesity
Peter T. Katzmarzyk, Sean Wharton, Fatima Cody Stanford, and Daniel G. Aaron
PART 3: LIFESTYLE IN THE MANAGEMENT OF OBESITY: BEHAVIORAL MODIFICATION, DIET, AND EXERCISE
14. Best Practices: Obesity and the Primary Care Providers
Christine Gallagher, Donna H. Ryan, and William Dietz
15. In-Person Behavioral Approaches for Weight Management
Jena S. Tronieri and Thomas A. Wadden
16. Behavioral Interventions Delivered Remotely
Christoph Höchsmann and Corby K. Martin
17. Cultural Considerations in Behavioral Therapy for the Management of Obesity
Robert L. Newton, Jr., Elva Arredondo, Patricia Dionicio, and Noe C. Crespo
18. Diet Composition and Weight Loss: Is a Calorie a Calorie?
Kevin D. Hall
19. Circadian Rhythms and Weight Loss: Timed Food Intake
Emily N.C. Manoogian, Nikko R. Gutierrez, Erika Padilla, and Michael J. Wilkinson
20. Comparison of Modern-Millennial Diets
Monica Dinu, Daniela Martini, Francesco Sofi, Mauro Serafini, Marisa Porrini, and Donato Angelino
21. Dietary Energy Density and Its Contribution to Weight Control
Faris M. Zuraikat and Barbara J. Rolls
22. Dietary Patterns as a Basis for Diet Selection
Catherine M. Champagne
23. Physical Activity and Weight Loss: Volume, Intensity, and Mode
John M. Jakicic and Renee J. Rogers
24. Modifying Sedentary Behavior for the Prevention and Treatment of Obesity
Bethany Barone Gibbs
25. Preventing Weight Regain after Weight Loss
Stephen D. Anton and Michael G. Perri
26. Personalized and Precision Nutrition in the Management of Obesity: Can We Tailor the Treatment to the Patient?
George Thom and Mike Lean
PART 4: MEDICATIONS IN THE MANAGEMENT OF OBESITY
27. Drug-Associated Weight Gain and Clinical Alternatives
Barbara Ameer and Michael A. Weintraub
28. Mechanisms of Drug Action in Obesity
M. Furkan Burak, Nawfal W. Istfan, and Caroline M. Apovian
29. Metabolic Effects of Progressive Weight Loss
Faidon Magkos
30. Older Drugs Used to Manage Obesity: Sympathomimetics and Orlistat
Frank L. Greenway and George A. Bray
31. Serotonergic Drugs for Treating Obesity
Mireille J. Serlie
32. Antidiabetic Drugs That Reduce Weight and Are Cardioprotective
Carolina M. Perdomo, Javier Escalada, and Gema Frühbeck
33. Approved Combination Agents: Phentermine/Topiramate
W. Timothy Garvey
34. Approved Combination Agents: Naltrexone-Bupropion
Igho J. Onakpoya and Carl J. Heneghan
35. Drugs That Affect Body Weight: The Glucagon-Like Peptide-1. Agonists
Randa Ghazal Asswad and John P.H. Wilding
36. Hydrogels in the Treatment of Obesity
Frank L. Greenway
37. Dual and Triple-Action Peptides
Thinzar Min and Stephen C. Bain
38. Antiobesity Medications on the Horizon
Sarah R. Barenbaum and Louis J. Aronne
39. Treatments for Rare Forms of Genetic Obesity
Joan C. Han, Nandini Basuray, and Andrea M. Haqq
40. Special Issues in Using Medications in Children and Adolescents
Jaime M. Moore, Stephen R. Daniels, and Claudia K. Fox
41. Dietary Supplements and Weight Management
Carol J. Haggans, Rebecca B. Costello, Leila G. Saldanha, Abby G. Ershow, and William T. Cefalu
PART 5: SURGICAL INTERVENTIONS FOR OBESITY
42. Historical Overview of Metabolic and Bariatric Surgery
Henry Buchwald
43. Overview: Current Metabolic Operations and Long-Term Outcomes
Robert C. Ross, Vance L. Albaugh, Ali Aminian, and Philip R. Schauer
44. Effects of Metabolic Surgery on Type 2. Diabetes
Pia Roser, Ghassan Chamseddine, and Francesco Rubino
45. Cardiovascular Outcomes in Metabolic Surgery
Wen Hui Tan, Tammy Kindel, Steven Nissen, and Philip R. Schauer
46. Effect of Bariatric Surgery on Cancer
Justin C. Brown, Andrea M. Stroud, Priya A. Rajdev, and Bruce M. Wolfe
47. Bariatric Surgery in Pediatric Patients
Sarah Ogle and Thomas Inge
48. Other Bariatric Procedures: Nerve Stimulation, Gastric Balloons, Intestinal Liners, and Others
Cullen F. Roberts, Colston Edgerton, and Scott A. Shikora
Index
Biography
George A. Bray, MD, MACP, MACE, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States
Claude Bouchard, PhD, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States
Peter T. Katzmarzyk, PhD, FACSM, FTOS, FAHA, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States
John P. Kirwan, PhD, Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States
Leanne M. Redman, PhD, Reproductive Endocrinology and Women’s Health Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, United States
Philip R. Schauer, MD, Metamor Institute, Pennington Biomedical Research Center, Baton Rouge, Louisiana
