Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery, and Therapy, 1st Edition (Hardback) book cover

Handbook of Personalized Medicine

Advances in Nanotechnology, Drug Delivery, and Therapy, 1st Edition

Edited by Ioannis S. Vizirianakis

Jenny Stanford Publishing

1,560 pages | 48 Color Illus. | 88 B/W Illus.

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pub: 2014-02-12
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Description

This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Reviews

The development of the Handbook of Personalized Medicine is timely. Medicine and health have evidently moved on and continue to progress and develop at a pace. Gone are the days, perhaps, when medical treatments for patients were developed and designed as a ‘one size fits all’ solution. Much more is now understood about individual differences in the way in which diseases develop and specifically also about individual differences in response to treatments. … This book represents an exceedingly comprehensive and detailed account of these developments, with the aim of integrating certain of these approaches into every day clinical practice. … its structure is clearly laid out, contributing authors clearly stated and the periodic use of comprehensive tables, graphs, and colour figures undoubtedly improve its understanding. … This book has been a massive undertaking to produce and portrays a journey from the most basic considerations through to the medical practice of the future."

David Fishwick, Occupational Medicine Journal

Table of Contents

Implementation of pharmacogenetics in evidence-based medicine

Pharmacotyping-based drug prescription

Pharmacogenetics-guided antithrombotic therapy

Translational bioinformatics and systems biology

Predictive genomic signatures

Personalizing stem cell therapeutic potential

RNAi nanomedicines

Nanotechnology advancements for personalized medicine

Pharmacogenetics and pharmacovigilance

Genetic variability of cytochrome P450 drug metabolizing enzymes

Developmental Pharmacology and Pediatric Drug Dosing

Functional mapping of drug response

Predictive molecular signatures

Information-based medicine

Simcyp population-based ADME simulator

The Coriell personalized medicine collaborative

Drug bioavailability and gene profiling

Safety assessment in nanotechnology

In vivo pharmacology

Biostatistics and text mining

Intersection of pharmacology, imaging, and genetics

Boron Neutron Capture Therapy

Personalized medicine in breast cancer

Personalized therapy of metabolic diseases

Molecular biomarkers and imaging

Pharmacogenomics of drug-induced hepatotoxicity

Education programs for pharmacogenomics

Computerized clinical decision support systems for prescribing

Therapeutic drug monitoring

Cost-effectiveness of pharmacogenomics

Ethical and legal pharmacogenomics issues

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
MED072000
MEDICAL / Pharmacy
SCI010000
SCIENCE / Biotechnology
SCI086000
SCIENCE / Life Sciences / General