1st Edition

Handbook of Solubility Data for Pharmaceuticals

By Abolghasem Jouyban Copyright 2010
552 Pages 5 B/W Illustrations
by CRC Press

552 Pages
by CRC Press

Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive database of solubility for pharmaceuticals in mono... Read more

Introduction

Solubility Determination Methods

Aqueous Solubility Prediction Methods

Solubility Prediction in Organic Solvents

The Accuracy Criteria in Solubility Calculation Methods

Acceptable MPD Range in Solubility Calculations

Solubilization of Drugs by Cosolvency

Review of Cosolvency Models

Concluding Remarks

Solubility Data in Organic Solvents

Solubility Data in Binary Solvent Mixtures

Solubility Data in Ternary Solvent Mixtures

Subject Index

Drug Index

Solvent Index

CAS Number

List of Abbreviations

References appear at the end of each chapter.

Biography

Abolghasem Jouyban is a professor of pharmaceutical analysis at Tabriz University of Medical Sciences in Iran.