232 Pages
38 B/W Illustrations
by
CRC Press
232 Pages
by
CRC Press
Also available as eBook on:
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is proving to be the most protean of all transcription... Read more
The NF-kB Pathway: A Paradigm for Inducible Gene
Expression, S. Ghosh
Structural Aspects of NF-kB and I•B Proteins, A. K. Moorthy, T. Huxford, and G. Ghosh
Regulation of IKK, H. Häcker and M. Karin
Control of NF-kB Activation by Ubiquitination, S. C. Ley and Y. Ben-Neriah
Regulation of Nuclear NF-kB Action: A Key Role for Posttranslational Modification, L.F. Chen and W. C. Greene
NF-kB in the Innate Immune System, M. S. Hayden and S. Ghosh
NF-kB in the Adaptive Immune System: Lymphocyte Survival and Function, M. S. Hayden and S. Ghosh
NF-kB and IKK as Key Mediators of Inflammation and Oncogenic Progression, A. S. Baldwin
NF-kB and Associated Human Genetic Pathologies, A. Israël
Regulating the Master Regulator NF-kB: From Natural Strategies to Rationally Designed Superdrugs, S. Withoff, V. Tergaonkar, and I. M. Verma
Index
Expression, S. Ghosh
Structural Aspects of NF-kB and I•B Proteins, A. K. Moorthy, T. Huxford, and G. Ghosh
Regulation of IKK, H. Häcker and M. Karin
Control of NF-kB Activation by Ubiquitination, S. C. Ley and Y. Ben-Neriah
Regulation of Nuclear NF-kB Action: A Key Role for Posttranslational Modification, L.F. Chen and W. C. Greene
NF-kB in the Innate Immune System, M. S. Hayden and S. Ghosh
NF-kB in the Adaptive Immune System: Lymphocyte Survival and Function, M. S. Hayden and S. Ghosh
NF-kB and IKK as Key Mediators of Inflammation and Oncogenic Progression, A. S. Baldwin
NF-kB and Associated Human Genetic Pathologies, A. Israël
Regulating the Master Regulator NF-kB: From Natural Strategies to Rationally Designed Superdrugs, S. Withoff, V. Tergaonkar, and I. M. Verma
Index
Biography
Sankar Ghosh
