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Handbooks in Pharmacology and Toxicology


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Phospholipase A2 in Clinical InflammationMolecular Approaches to Pathophysiology

Phospholipase A2 in Clinical InflammationMolecular Approaches to Pathophysiology

1st Edition

Keith B. Glaser, Peter Vadas
August 03, 1995

Phospholipase A2 in Clinical Inflammation presents an up-to-date topical review of the biochemistry, molecular biology, and biology of mammalian phospholipase A2 (PLA2). The emphasis of this monograph is on the current aspects of PLA2 research using molecular approaches to investigate PLA2 ...

Serotonin and Gastrointestinal Function

Serotonin and Gastrointestinal Function

1st Edition

Timothy S. Gaginella, James J. Galligan
July 25, 1995

Serotonin and Gastrointestinal Function provides a comprehensive review of current research into the mechanisms by which serotonin acts on gastrointestinal tissues. This book covers neurochemistry, physiology, pharmacology, and clinical issues relevant to serotonin in the gastrointestinal tract. ...

Taxol Science and Applications

Taxol: Science and Applications

1st Edition

Matthew Suffness
May 25, 1995

This volume brings together all aspects of TAXOL® research, development, and clinical use. It provides comprehensive knowledge of the compound and a perspective of the complex interrelationships needed for its development and production. Each chapter is written by an authority in the field. ...

Endothelin Receptors From the Gene to the Human

Endothelin Receptors: From the Gene to the Human

1st Edition

Robert R. Ruffolo, Jr.
May 19, 1995

Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are...

Human Growth Hormone Pharmacology Basic and Clinical Aspects

Human Growth Hormone Pharmacology: Basic and Clinical Aspects

1st Edition

Kathleen T. Shiverick, Arlan L. Rosenbloom
March 09, 1995

This book addresses a wide range of basic and clinical issues in the physiology and pharmacology of growth hormone. The volume is organized like a textbook. It begins with factors contributing to GH gene expression, the functional relationships of the GH receptor, molecular biological analysis of ...

Biological Approaches to Rational Drug Design

Biological Approaches to Rational Drug Design

1st Edition

David B. Weiner, William V. Williams
December 22, 1994

This book exploits an understanding of disease pathogenesis by applying a variety of biological agents to therapy. It provides a broad overview of the current methodologies being applied to biological approaches to rational drug design and in depth analyses of progress in this specific field....

Genomic and Non-Genomic Effects of Aldosterone

Genomic and Non-Genomic Effects of Aldosterone

1st Edition

Martin Wehling
December 14, 1994

This exciting new book summarizes the known features of both the more traditional genomic aldosterone effects and those modern aspects of non-genomic aldosterone effects discovered within the past few years. International specialists contribute to the scholarship on these issues. Chapters include ...

Chemical and Structural Approaches to Rational Drug Design

Chemical and Structural Approaches to Rational Drug Design

1st Edition

David B. Weiner, William V. Williams
November 28, 1994

This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. ...

Angiotensin II Receptors

Angiotensin II Receptors

1st Edition

Robert R. Ruffolo, Jr.
September 06, 1994

This unique reference set provides a broad-based, in-depth presentation on angiotensin II receptors, from the genes that encode them to the responses they mediate in humans. The books emphasize known and potential therapeutic applications of the antagonists of angiotensin II receptors and the ...

Direct and Allosteric Control of Glutamate Receptors

Direct and Allosteric Control of Glutamate Receptors

1st Edition

Michael G. Palfreyman, Ian J. Reynolds, Phil Skolnick
August 16, 1994

Direct and Allosteric Control of Glutamate Receptors describes in detail recent research that has demonstrated that glutamate receptors are subject to numerous modulatory controls. Significant new insights into the physiology and pathophysiology of the nervous system have been obtained by these ...

Angiotensin II Receptors

Angiotensin II Receptors

1st Edition

Robert R. Ruffolo, Jr.
July 13, 1994

This unique reference set provides a broad-based, in-depth presentation on angiotensin II receptors, from the genes that encode them to the responses they mediate in humans. The books emphasize known and potential therapeutic applications of the antagonists of angiotensin II receptors and the ...

Peroxisome Proliferators Unique Inducers of Drug-Metabolizing Enzymes

Peroxisome Proliferators: Unique Inducers of Drug-Metabolizing Enzymes

1st Edition

David E. Moody
July 12, 1994

Induction of drug (xenobiotic)-metabolizing enzymes is a common biological response to xenobiotics, the mechanisms and consequences of which are important in academic, industrial, and regulatory areas of pharmacology and toxicology. This monograph, for the first time, has brought together ...

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