Hemodialysis Membranes: For Engineers to Medical Practitioners, 1st Edition (Hardback) book cover

Hemodialysis Membranes

For Engineers to Medical Practitioners, 1st Edition

By Sirshendu De, Anirban Roy

CRC Press

214 pages | 111 B/W Illus.

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pub: 2017-05-02
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Book initiates with introductory material to hemodialysis technology and its historical evolution and later on divulging into the field of biomaterials. With this background, the book discusses selection criteria of a suitable biomaterial for synthesis of haemodialysis membranes along with illustration of a complete indigenous, low cost technology for spinning of haemodialysis fibres. Well illustrated description of instruments used for membrane characterization and biomedical engineering is also provided at suitable junctures to effectively present the concept including worked out examples. Present title can be a good textbook as well as a research material for membrane as well as biomedical engineering curricula and provides coverage for appropriate undergraduate and graduate students interested in hemodialysis membranes.

Table of Contents

1.Kidney Function and Uremia

Kidney Function and Micturition

Quantifying Kidney Performance

Renal Failure : Types and Causes

Kidney Failure - Uremic Toxicity

Conclusion - Treatment for Renal Failure Patients

2. Evolution of Hemodialysis Technology

Hemodialysis Technology

Membrane technology

Hemodialysis - state of art and basics

Hemodialysis transport mechanisms

Hemodialysis membranes - material development


3. Biocompatibility and Biomaterials

Biocompatibility and Biomaterials - Definition

History of biomaterials

Essential properties of biomaterials

Biocompatibility in case of dialysis membranes

Essential Equipments for Analyzing Biocompatibility


4. Selection of Material for Dialysis Membrane


Materials and Methods

Selection of best material

Comparison of present study with state of art literature


5. Spinning of Dialysis Grade Membranes


Materials and Methods

Results and discussion


6. Post Processing of Dialysis Membranes


Experimental Section

Results and discussion


7. Mathematical Modeling of Dialysis


Mathematical models

Mathematical method to find post dialysis urea concentration

Regional Blood Flow (RBF) Model

Holistic View: Hemodialyzer Modeling


8. Economics of Dialyzer Manufacturing : Commercialization


Customer segmentation

Plant Layout, Design and Production

Business plan, key activities and key resources

Financial analysis

Prototypes developed


9. Conclusion : Future Trends and Scope

Future trends in dialysis research

Water Requirements and Standards

Dialyzer reuse and India

Dialyzer Reuse : Steps

Holistic Overview


About the Authors

Dr. Sirshendu De is professor of Department of Chemical Engineering, Indian Institute of Technology Kharagpur (IIT KGP). He completed his undergraduate (1986-90), masters (1991-92) and PhD (1993-1997) degrees all from IIT Kanpur. Having completed his PhD he joined IIT KGP as Visiting Faculty in 1997 and rose to Associate Professor in 2002, finally becoming a Professor in 2007. Presently he is the Head of Department of Chemical Engineering. Prof. De is an eminent chemical engineer in India. He maintains national and international visibility through his innumerable international publications (232), patents (15), books (7) and book chapters (10) and 3 technology transfers. Apart from developing low cost spinning of both dialysis membranes as well as hollow fibers for water treatment and other industrial use, some of other innovations by Prof. De include ultra low cost filter for removal of arsenic from drinking water, extraction of polyphenols from green tea leaves and processing of packaged tender coconut water with high shelf life without any additive and preservative. Prof. De has been awarded with prestigious Shanti Swarup Bhatnagar (2011), the highest scientific honour of India. He has also been recipient of Innovation Award 2015 by Indian Desalination Association (south zone), National Award (Govt. of India) for Technology Innovation in various Field of Petrochemicals and Downstream Plastic Processing Industry – 2015, Department of Science and Technology (Govt. of India) - Lockheed Martin - Gold Medal - Top 10 Innovation Award 2015 - IC2 Business Development Support, NASI Reliance award (2013), Herdilia Awards (2010) to name a few. He is a fellow of INAE and NASI. Presently he is INAE Chair Professor and is serving as the Head of Department of Chemical Engineering.

Anirban Roy completed his undergraduate training in Chemical Engineering from Heritage Institute of Technology, Kolkata, in 2007 and Masters in Chemical Engineering from Jadavpur University, Kolkata in 2009. He had a brief stint as a research assistant at the University of Rhode Island from 2009-2011 and worked as a consultant engineer at M.N. Dastur and Co Pvt. Ltd for TATA Steel, Jindal and Vizag steel. He joined the PhD program at Department of Chemical Engineering, IIT Kharagpur, under the guidance of Prof. Sirshendu De, in 2012 and has been working on membrane separations with specialization on hemodialysis membranes. He is involved in developing the indigenous process design of hemodialysis grade hollow fibers as topic of his PhD dissertation. He has published 9 papers in international journals and has 10 conference publications (international and national). He has also filed 3 Indian and 1 US patent. Anirban has been the recipient of the "Young Innovator of India 2015" award in the Make In India conclave held at IIT Bombay, "National Award (Govt. of India)" for Technology Innovation in various Field of Petrochemicals and Downstream Plastic Processing Industry – 2015, Department of Science and Technology (Govt. of India) - Lockheed Martin - Gold Medal - Top 10 Innovation Award 2015 - IC2 Business Development Support, IChemE Global Award (Top 5 shortlist) for Dhirubhai Ambani Award for Outstanding Chemical Engineering Innovation for Resource-Poor People and Simulanis Research Challenge - Top 3 Innovations in India. His research interests include biomedical applications of membrane technologies, polymer blend thermodynamics, rheology and clarification of food products and water treatment.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
MEDICAL / Nephrology
SCIENCE / Chemistry / Industrial & Technical