This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies.
Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique.
This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.
Table of Contents
Role of St.-John’s Wort (Hypericum perforatum L.) in the Management of Diabetes and Neurological Disorders
Yusuf Ozturk, Ozgur Devrim Can, and Umide Demir-Ozkay
A Potential Natural Product Combination Targeting Memory Disorders
Manju Bhaskar, Meena Chintamaneni, and Veeranjaneyulu Addepalli
Phytotherapeutic Agents in Epilepsy
Herbal Medicines in Neuropsychiatric Illness: The Case of L-Stepholidine
Nitin Sati, Kedar S. Prabhavalkar, Sridhar N., and Lokesh K. Bhatt
Potential of Curcuma longa and Withania Somnifera for Diabetes and Associated Neurological Comorbidities
Suruchi Verma, Amitabha Dey, and Vikas Kumar
Migraine: Management and Treatment with Herbal Drugs
D. K. Arulmozhi, Yogesh A. Kulkarni, Addepalli Veeranjaneyulu, and R. S. Gaud
Complications of Diabetes and Role of a Citrus Flavonoid Nobiletin in Its Treatment
L. K. Bhatt, N. A. Parkar, V. Addepalli, and R. S. Gaud
Diabetes and Phytopharmaceuticals: Translational Pharmacology Perspective
Priyanka Ingle-Jadhav, Trupti R. Angolkar, and Ginpreet Kaur
Natural Products as Effective Treatment Option for Depression
Yogesh A. Kulkarni, Kalyani H. Barve, and Ginpreet Kaur
Medicinal Plants Research
Mila Emerald and David Marrero
Vikas Kumar, PhD, is currently working in research and product development at the National Center for Natural Products Research (NCNPR), School of Pharmacy, at the University of Mississippi. He was formerly an Innovation Specialist at DD Innovations, Inc., Edina, Minnesota, USA, and Associate Professor of Pharmacology at the Neuropharmacology Research Laboratory, Department of Pharmaceutics, at the Indian Institute of Technology (Banaras Hindu University) in Uttar Pradesh, India. He has published more than 150 papers in peer-reviewed journals as well as four books and eight book chapters. He has visited Canada, Germany, France, China, Nepal, Thailand, Singapore, South Africa, Italy and UAE to enhance his professional experience at various capacities. He is life member of several professional associations and serves as a member of editorial boards of many peer-reviewed international journals. He previously worked successfully and productively in the pharmaceutical industries viz. Lupin Research Park, Pune, and Indian Herbs Research & Supply Co. Ltd., Saharanpur, India. Based on his research findings, Indian Herbs Ltd. successfully launched a product viz. MoodOn® (as a herbal antidepressant and mood enhancer) into the Indian market in collaboration with Bergen Healthcare, a division of Alkem Laboratories Ltd., Mumbai. Currently, MoodOn® is sold under trade name EnMood® (http://www.indianherbs.org/mEnMood.htm). He also has scientific collaborations with Dr. Willmar Schwabe GmbH & Co. KG, Germany.
Dr. Kumar has received Sami Khatib Gold Medal for being a topper in B.Pharm. and Servier Young Investigators’ Award instituted by Institutet de Researches Internationales Servier, France. He is also recipient of the coveted institutional and globally reputed Rashtriya Gaurav Award in 2011 for his achievements in the field of science and technology. Dr. Kumar has obtained his PhD degree from IIT (BHU), Varanasi in 2001 after completing MPharm and BPharm from Gulbarga University in 1997 and 1995 respectively.
Addepalli Veeranjaneyulu, PhD, is presently serving as Associate Dean and Senior Professor and Head of Pharmacology at SPP, the School of Pharmacy and Technology Management (SPTM), NMIMS, Mumbai, India. He was formerly a Visiting Scientist/Professor at the International Institute of Medical Sciences in China (from 2006-07) under the auspices of Canadian Heart Foundations. Dr. Addepalli has 16 years of industrial new drug discovery research experience, with over six years as Assistant Director (Pharmacology and Quality Assurance) at NCER, at Lupin Research Park, Pune, India, and over ten years as Research Executive (Pharmacology and Pharmacokinetics) in IDPL R&D, Hyderabad, India. He has 18 years of teaching experience. His research interests are cardiovascular dysfunction and other complications in diabetes; receptor pharmacology; serotonergic receptors; and modulatory roles in migraine, psychosis, and other CNS disorders. He was the Principal Investigator for several projects funded by CSIR, UGC, AICTE, and pharma industrial/academia collaborative projects funded by various pharma companies. He is a member of several national and international professional bodies and is an editorial board member and reviewer for several journals journals. Dr. Addepalli has over 180 research publications in national and international journals with three industrial patents to his credit. He also presented papers at international and national conferences and seminars and also chaired scientific sessions.
"Our societies find themselves burdened with a growing number of CNS disorders and diabetes, and augmentation of the present therapies by incorporating medicines from natural sources is desirable. Dr. Veeranjaneyulu and Dr. Kumar deserve kudos for putting together this book of thoughtful reviews on plants for treatment of major disorders of central nervous systems and diabetes. Written by several scientists, this book thus fulfills the need for a quick reference and will certainly rekindle interest in this area. . . . This book will be of immense value to researchers in the area and I congratulate both editors for this book."
—From the Foreword by Dr. Madhu Dikshit, FNA, FASc, FNASc, JC Bose National Fellow/Director, CSIR-Central Drug Research Institute, India
"A valuable guide for modern drug hunters and pharmaceutical industries interested in identification of novel pharmacological therapies for meeting the treatment needs of patients suffering from, or at risk of, diabetes and other non-communicable diseases. Information summarized in this book will certainly be very useful in translating the knowledge and knowhow of practitioners of traditionally known systems of medicine in terms of modern molecular sciences. . . . It cannot be overemphasized that such publications are necessary for evolution of experimental evidence-based holistic medicine."
—Dr. Shyam Sunder Chatterjee, Retired Head of Pharmacology Research Laboratories; Dr. Willmar Schwabe GMBH & Co.KG, Karlsruhe, Germany