1st Edition

High-Resolution Mass Spectrometry and Its Diverse Applications Cutting-Edge Techniques and Instrumentation

    276 Pages 15 Color & 45 B/W Illustrations
    by Apple Academic Press

    276 Pages 15 Color & 45 B/W Illustrations
    by Apple Academic Press

    This informative book offers a wide range of knowledge on the technologies and applications of the cutting-edge field of high-resolution mass spectrometry (HRMS) in different areas of analysis. HRMS has changed the nature of experimentation and investigation in so many analytical realms. Determining exact mass determination, high resolution, and specificity—via the special features provided by HRMS instruments—is now possible for determining the composition of the analyte of interest, both qualitatively and quantitatively.

    High-Resolution Mass Spectrometry and Its Diverse Applications: Cutting-Edge Techniques and Instrumentation begins with an overview of the basic instrumentation techniques and goes on to present research on diverse new uses of HRMS in clinical testing, such as for therapeutic drug designing, discovery, and development; in forensic studies and investigations; in quality management systems; for analysis of pesticides; for analysis of single cells; in analysis of fossil fuels; for use in space and planetary science; and more.

    Chapters relay how HRMS plays an important role in the structure elucidation and unknown determination in many fields and is a great measure to be used for quantitative analyses. The book considers how these properties make the technique a strong aid in many areas.

    This volume highlights how HRMS can be a useful tool for scientists and researchers, faculty and students, and industry professionals in many scientific areas of study.

    1. HRMS: Fundamental Concepts, and Instrumentation

    Karthik Varma, Sreeraj Gopi, and Józef T. Haponiuk

    2. Identification and Structure Elucidation of Compounds: Deleting ‘Un’ from the Unknowns

    Joby Jacob, Shintu Jude, and Sreeraj Gopi
    3. HRMS: The Cutting-Edge Technique in Clinical Laboratory

    Karthik Varma, Sreeraj Gopi, and Józef T. Haponiuk

    4. Therapeutic Drug Designing, Discovery, and Development by HRMS

    A. Rajeswari, et al.

    5. Quality Management in a Feasible Manner Through HRMS

    Shintu Jude and Sreeraj Gopi

    6. HRMS for Forensic Studies and Investigations

    Akhila Nair, Józef T. Haponiuk, and Sreeraj Gopi

    7. HRMS for the Analysis of Pesticides

    E. Jackcina Stobel Christy, Augustine Amalraj, and Anitha Pius

    8. Applications of HRMS in Environmental Impact Assessment

    S. Subasini, et al.

    9. Single Cell Analysis Methods Based on Mass Spectrometry

    Reshma V. R. Nair

    10. Discoveries of HRMS Beyond the Globe: Application in Space and Planetary Science

    Akhila Nair, Józef T. Haponiuk, and Sreeraj Gopi

    11. Application of High-Resolution Mass Spectrometry in the Analysis of Fossil Fuels

    Xueming Dong and Xing Fan


    Sreeraj Gopi, PhD, is an industrial scientist working in the areas of natural products, isolation, and establishing biological activities. He has published more than 100 international articles and has filed more than 75 international patents. A fellow of the Royal Society of Chemistry and a fellow of the American College of Nutrition, USA, Dr. Gopi is co-author of many books and is an invited speaker at many universities. Dr. Gopi is serving as an adjunct professor at many universities, including Stockholm University, Sweden; Siberian Federal University, Russia; Mahatma Gandhi University, India; and Gdansk University of Technology, Poland.

    Sabu Thomas, PhD, is currently the Vice-Chancellor of Mahatma Gandhi University and the Founder Director and Professor of the International and Inter University Centre for Nanoscience and Nanotechnology, Kottayam, India. He is also a full professor of Polymer Science and Engineering at the School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, India. Professor Thomas is an outstanding leader with sustained international acclaim for his work in nanoscience, polymer science and engineering, polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites and nanocomposites, nanomedicine, and green nanotechnology. Dr. Thomas has been conferred an Honoris Causa DSc from the University of South Brittany, France, and University of Lorraine, France. Very recently he was awarded the Foreign Fellow of the European Academy of Sciences (EurASc) and was listed on Stanford University’s list of top 2% of scientists in the world. He has received many national and international awards, and he has published over 1000 peer-reviewed research papers, reviews, and book chapters. He has co-edited 80 books, and he is the inventor of more than five patents (granted: 4, filed: 11).

    Augustine Amalraj, PhD, is currently working as a Deputy Manager in the Department of Research and Development in Plant Lipids Private Limited, Cochin, India. He obtained his doctoral degree in chemistry from Gandhigram Rural Institute (Deemed University), Gandhigram, Tamil Nadu, India. His research interests are in applied chemistry, food chemistry, natural product chemistry, environmental chemistry, chemosensors, and polymer and nanocomposite materials. He has published more than 50 research articles in international journals as well as 15 book chapters.

    Shintu Jude is working as Assistant Manager in Research and Development Department at Plant Lipids Private Limited, Cochin, India. Mrs. Jude has completed her postgraduation at Mahatma Gandhi University, India. She is working on mass spectroscopic instruments for natural products and metabolites. She has published more than 20 research articles and 10 book chapters.