1st Edition

Hydrophilic Polymer Coatings for Medical Devices

By Richard J. LaPorte Copyright 1997
    198 Pages
    by CRC Press

    198 Pages
    by CRC Press

    This new text provides a practical guide to hydrophilic polymer coatings technology for applications in a wide range of medical materials and devices. It concisely provides both the scientific basics of this class of polymers and the up-to-date information needed for product development and evaluation, processing, manufacturing, and regulatory compliance. More than fifty schematics illustrate materials, processes, and equipment. The entire presentation is oriented to the practical needs of personnel involved in product development and evaluation, process engineering, and manufacturing management.

    Each chapter ends with a Citations section. Preface The Property of Wettability
    Factors Affecting Surface Tensions and Contact Angles
    Measuring Surface Tensions and Contact Angles
    Wettability of Polymer Surfaces
    Hydrophilicity and the Structure of Hydrophilic Systems
    Contribution of Molecular Structure
    Aspects of the Network Structure
    Aspects of the Surface Structure
    Factors Affecting Swelling Characteristics
    Quantifying Useful Properties
    Common Hydrophilic Polymers
    Synthetic Hydrophilic Polymers
    Hydrophilic Polymers Prepared from Naturally Occurring Materials
    Considerations for Development and Manufacture
    Overview of Coating Technology
    Product-, Process-, and Facility-Related Considerations
    Surface Preparation
    Cleaning Operations
    Plasma Treatment
    Other Methods of Surface Treatment
    Coating Application and Curing Techniques
    Methods of Application
    Methods of Curing
    Additional Technologies
    Surface Analysis, Testing Methods, and Process Monitoring
    Surface Analysis
    Testing Methods
    Regulatory and Safety Concerns
    Regulatory Considerations
    Safety Considerations
    Lubricious Coatings
    Drug Delivery Systems
    54 Figures, 4 Tables


    Richard J. LaPorte