Hydroxyapatite Coatings for Biomedical Applications: 1st Edition (Paperback) book cover

Hydroxyapatite Coatings for Biomedical Applications

1st Edition

Edited by Sam Zhang

CRC Press

469 pages | 329 B/W Illus.

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Hydroxyapatite coatings are of great importance in the biological and biomedical coatings fields, especially in the current era of nanotechnology and bioapplications. With a bonelike structure that promotes osseointegration, hydroxyapatite coating can be applied to otherwise bioinactive implants to make their surface bioactive, thus achieving faster healing and recovery. In addition to applications in orthopedic and dental implants, this coating can also be used in drug delivery. Hydroxyapatite Coatings for Biomedical Applications explores developments in the processing and property characterization and applications of hydroxyapatite to provide timely information for active researchers and newcomers alike.

In eight carefully reviewed chapters, hydroxyapatite experts from the United States, Japan, Singapore, and China present the latest on topics ranging from deposition processes to biomedical applications in implants and drug delivery.

This book discusses:

  • Magnetron sputtering and electrochemical deposition
  • The modification of hydroxyapatite properties by sol–gel deposition to incorporate other elements found in natural bones, such as zinc, magnesium, and fluorine
  • The use of pure hydroxyapatite in drug delivery applications
  • The growth or self-assembly of hydroxyapatite on shape memory alloy
  • Hydroxyapatite composite coatings—with carbon nanotubes, titanium dioxide (TiO2), and others—on the titanium alloy

Offering valuable insights and a wealth of data, including numerous tables and figures, this is a rich source of information for research on hydroxyapatite coatings. Each chapter also covers material that provides an accessible stepping stone for those who are new to the field.


"This is a well-written book containing important up-to-date information pertaining to the fabrication, properties, and applications of hydroxyapatite coatings. I highly recommend this book to engineers and researchers working in the field, particularly graduate students."

—Paul K. Chu, City University of Hong Kong

"Hydroxyapatile is indeed one of the important materials in biology, medical, and clinical studies. Of course, coating of this important material is a central issue in its application. This book nicely picks up important subjects in the corresponding field and comfortably organizes chapters with important contents."

—Katsuhiko Ariga, NIMS International Center for Materials Nanoarchitectonics (MANA), Japan

Table of Contents

Magnetron Sputtering Deposition of Chemically Modified Hydroxyapatite

Eng San Thian and Cleo Choong

Electrochemical Deposition of Hydroxyapatite and Its Biomedical Applications

Toshiki Miyazaki and Masakazu Kawashita

Simultaneous Incorporation of Magnesium and Fluorine Ions in Hydroxyapatite Coatings on Metallic Implant for Osseointegration and Stability

Yanli Cai, Sam Zhang, Soon-Eng Ong, Xianting Zeng, and Wilson Wang

Zinc- and Fluorine-Doped HA Coatings via Sol–Gel Method

Kui Cheng and Wenjian Weng

Biomimetic Hydroxyapatite Materials for Therapeutic Delivery

Travelle W. Franklin-Ford, Darilis Suarez-Gonzalez, Jae Sung Lee, and William L. Murphy

Apatite-Coated Polymer Template for Implant and Drug Delivery

Zhe Zhang, Sam Zhang, and Lei Shang

Biofunctionalization of NiTi Shape Memory Alloy Promoting Osseointegration by Chemical Treatment

Yanli Cai, Xianjin Yang, Zhenduo Cui, Minfang Chen, Kai Hu, and Changyi Li

Investigation and Application of HA Composite Coating on the Ti Alloy

Wei Qiang, Zhao Jin, Zhang Lijun, Liu Shimin, and Liang Yanqin


About the Editor

Professor Sam Zhang Shanyong, better known as Sam Zhang, received his Ph.D. in ceramics from the University of Wisconsin-Madison in 1991, and is a tenured full professor at the School of Mechanical and Aerospace Engineering, Nanyang Technological University. Professor Zhang serves as editor-in-chief for Nanoscience and Nanotechnology Letters and principal editor for Journal of Materials Research (United States). He has been involved in processing and characterization of nanocomposite thin films and coatings for 20 years and has authored or coauthored more than 250 peer-reviewed international journal papers, 8 books, and 20 book chapters, and has guest edited more than 20 journal volumes. His book Materials Characterization Techniques (CRC Press 2008) has been adopted as a textbook by several universities. Other CRC Press books include:

For more information, see Professor Zhang’s page at Nanyang Technological University.

About the Series

Advances in Materials Science and Engineering

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
SCIENCE / Chemistry / General