326 Pages
by
CRC Press
328 Pages
by
CRC Press
Also available as eBook on:
A vast number of neural cell surface glycoproteins belonging to the immunoglobulin superfamily have been isolated over the past two decades. In functional studies, many of them have been shown to confer adhesive properties to cells and to play an important role in developmental processes such as cell migration and axon outgrowth. Recent observations implicate Ig superfamily adhesion molecules in... Read more
A. Structural Considerations
1. Structural Features of Neural Immunoglobulin Superfamily Adhesion Molecules
B. Interactions and Molecular Function
1. Molecular Interactions Involving Immunoglobulin Superfamily Adhesion Proteins 2. NCAM Polysialic Acid 3.
Signal Transduction, Neurite Growth and Ig-Superfamily Adhesion Molecules in the Vertebrate System 4. Ig Superfamily Kinases 5. Ig Superfamily Phosphatases
C. Role in Neural Development and Plasticity 1. Molecular Mechanisms of Growth Cone Guidance in the Vertebrate Nervous System 2. Genetic Analysis of the Fasciclin II Cell Adhesion Molecule Reveals Multiple Roles During the Generation of Neuronal Specificity 3. Neural Cell Adhesion Molecules in Activity-Dependent Plasticity
D. Role in Regeneration and Disease 1. Ig-Superfamily Molecules in Neural Regeneration in the CNS 2. Ig-Superfamily Molecules in Myelination and Regeneration in the Peripheral Nervous System 3. Medical Genetics of Ig Superfamily Molecules
1. Structural Features of Neural Immunoglobulin Superfamily Adhesion Molecules
B. Interactions and Molecular Function
1. Molecular Interactions Involving Immunoglobulin Superfamily Adhesion Proteins 2. NCAM Polysialic Acid 3.
Signal Transduction, Neurite Growth and Ig-Superfamily Adhesion Molecules in the Vertebrate System 4. Ig Superfamily Kinases 5. Ig Superfamily Phosphatases
C. Role in Neural Development and Plasticity 1. Molecular Mechanisms of Growth Cone Guidance in the Vertebrate Nervous System 2. Genetic Analysis of the Fasciclin II Cell Adhesion Molecule Reveals Multiple Roles During the Generation of Neuronal Specificity 3. Neural Cell Adhesion Molecules in Activity-Dependent Plasticity
D. Role in Regeneration and Disease 1. Ig-Superfamily Molecules in Neural Regeneration in the CNS 2. Ig-Superfamily Molecules in Myelination and Regeneration in the Peripheral Nervous System 3. Medical Genetics of Ig Superfamily Molecules
Biography
Peter Sonderegger
