1st Edition

Immune Modulating Agents



ISBN 9780824701031
Published October 17, 1997 by CRC Press
576 Pages

USD $385.00

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Book Description

Discussing the systemic immune response in the contexts of health, disease, and therapy, this unique resource-the only broadly based book of its kind available on the subject-offers comprehensive examinations of the pathways and agents that affect the human immune response and provides state-of-the-art presentations on practical methods of immune modulation.
Focuses on the immune response and modulation in infectious diseases, such as HIV, hepatitis, and parasitic infections and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer, and autoimmunity!
Written by over 50 international authorities representing distinguished institutions in nine countries, Immune Modulating Agents

  • introduces basic immunoregulatory mechanisms as homeostasis
  • details cytokines, cellular and humoral immune responses, and hematopoiesis
  • describes neuroendocrine - immune system interactions and the role of psychological stress on immune competence
  • delineates factors that influence disease susceptibility, including nutrition
  • covers drug delivery systems, gene therapy, organ transplantation, arthritis treatment, and vaccination strategies
  • shows how to design clinical trials using immune modulating agents
  • and more!
  • Table of Contents

    Immunomodulation

    The Immune System and Immune Modulation, François Hirsch and Guido Kroemer
    Molecular Mechanisms Controlling Immunoglobulin E Responses, Rachel L. Miller and Paul B. Rothman
    Idiotypes and T Cell Selection, Bjarne Bogen, Zlatko Dembic, and Siegfried Weiss
    In Vivo Modulation of Lymphohemopoietic Stem Cell Populations with Cytokines, Gerald de Haan and Gary Van Zant
    Hormones as Immune Modulating Agents, Istvan Berczi and Eva Nagy
    Transforming Growth Factor- : A Cytokine Paradigm, Michelle R. Frazier-Jessen, Nancy McCartney-Francis, and Sharon M. Wahl
    Psychological Stress and Immune Competence, Elizabeth A. Bachen, Anna L. Marsland, Stephen B. Manuck, and Sheldon Cohen
    Interleukin 12: A Potent Vaccine Adjuvant for Promoting Cellular Immunity and Modulating Humoral Immunity, Stanley F. Wolf


    Immunomodulating Agents in Disease

    Cytokine Immunomodulation of Infectious Diseases, Joseph F. Urban, Jr., Fred Douglass Finkelman, Terez Shea-Donohue, and William C. Gause
    Modulating Cytolytic Responses to Infectious Pathogens, Rebecca Pogue Caley and Jeffrey A. Frelinger
    Immunology of T Cells in AIDS: Dynamics Revealed by Eight-Color Flow Cytometry, Mario Roederer, Stephen C. De Rosa, Leonore A. Herzenberg, and Leonard A. Herzenberg
    Immunomodulation of Schistosomal-Induced Inflammation, Thomas F. Kresina
    Human Monoclonal Antibodies and Immune Modulation in Viral Hepatitis, Schistosomiasis, and HTLV Infection, Thomas F. Kresina, Garry A. Neil, and Steven K. H. Foung
    Nutrition and Immunity, Srinivas Denduluri and Ranjit K. Chandra
    Immunomodulating Agents in Gastrointestinal Disease, Samir A. Shah, Athos Bousvaros, and A. Christopher Stevens
    Immune Modulation in Sepsis, Janet M. J. Hammond and Peter D. Potgieter
    Interleukin 6: Role in the Pathogenesis of Cancer, Otoniel Martínez-Maza
    Neuroendocrine-Induced Immune Modulation and Autoimmunity, Terence Smith and Adrian K. Hewson


    Immunomodulating Agents in Therapy

    Antigen Delivery Systems Used to Induce Immunomodulation, M. Zahirul I. Khan, Ian G. Tucker, and Joan P. Opdebeeck
    Immunomodulation in Gene Therapeutics, Andreas Block, Susan S. Rich, Shu-Hsia Chen, and Savio L. C. Woo
    Cytokines, Apoptosis, and Immune Therapy in HIV Infection, Jerôme Estaquier and J. C. Ameisen
    Immune-Based Therapies for HIV-1 Infection and Its Complications, Timothy P. Flanigan and Michael Lederman
    Transplantation Tolerance, Microchimerism, and the Two-Way Paradigm, Thomas E. Starzl, Anthony J. Demetris, Noriko Murase, Massimo Trucco, Angus W. Thomson, Abdul S. Rao, and John J. Fung
    Immunomodulation of Cytokines and T Cells by Biologicals in Rheumatoid Arthritis, R. N. Maini and M. Feldmann
    Immunomodulation at Mucosal Surfaces: Prospects for the Development of Antiinfectious and Antiinflammatory Vaccines, Cecil Czerkinsky and Jan Holmgren
    New Statistical Designs for Clinical Trials of Immunomodulating Agents, Richard Simon

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