Immune System Accessory Cells provides a comprehensive survey of all types of antigen-presenting and accessory cells. Macrophages are emphasized through descriptions of different types of endocytosis, other major properties, and all basic and new information concerning macrophages as antigen-presenting cells. Other topics covered include the impact of the immunodeficient state on accessory functions, the evolutionary emergence of accessory functions, and the role of various cell types in defense reactions in major assemblages of Metazoa. The book also presents a chapter describing the phylogenetic aspects of accessory functions, which traces the first accessory cells during the evolution of living matter.
Immune System Accessory Cells is an excellent reference for immunologists, cell biologists, and others interested in developing an understanding of the roles of accessory cells in all facets of immune reactions.
Evolution of Immune Accessory Functions (P. Síma and V. Vetvicka). Ontogeny of the Stroma of Lymphoid Tissues (M. Holub). Endocytosis (V. Vetvicka). Antigen Processing (O. Werdelin and S. Mouritsen). Macrophages (V. Vetvicka and L. Fornusek). Antigen Presentation by Macrophages and Dendritic Cells (V. Vetvicka and L. Fornusek). Dendritic Cells as Accessory Cells (J. G. Tew, G.F. Burton, A. Masuda, Z.F. Kapasi, and A.K. Szakal). Langerhans' Cell Surface Molecules Involved in Accessory Functions (G.C. Mudde, T.T. Hansel, and C.A.F.M. Bruijnzeel-Koomen). The Dual Role of B Cells in Antigen Presentation: Induction and Regulation of Immune Responses (L. Leserman and J.-C. Grivel). Cell-Cell Interactions: In Situ Studies of Splenic Humoral Immune Responses (J.D. Laman, A.J.M. Van den Eertwegh, E. Claassen, and N. Van Rooijen). The Role of Accessory Cells in Positive and Negative Selection in the Thymus (P. Naquet and H. Lepesant). Function of Neutrophils in Host Defense and Immunity (G.D. Ross). Molecular Biology of Antigen Presentation (D. Gerlier, V. Calin-Laurens, P. Bertolino, and C. Rabourdin-Combe). Mediators Involved in Accessory Functions (U. Yamashita). Antigen Processing in B Lymphocytes: A Role for Stress Proteins (D.C. DeNagel and S.K. Pierce). Accessory Cells in Murine Immunodeficiencies (V. Vetvicka and L. Fornusek). Index.