This text has been written as a practical guide, based on the author’s experience over the last 40 years of daily clinical practice and aiming to place the modern approach to the management of infertility in the context of sound theory and evidence-based therapy. It provides the reader with a comprehensive classification of the causes of infertility, their investigation, and their management. This new edition covers many advances in the understanding and management of infertility and other updates to practice--for example, a greater understanding of the pathophysiology of ovarian aging and ovarian reserve testing; the classification of disorders of ovulation and management of polycystic ovary syndrome; the refinement of regimens for superovulation, improved embryo culture systems, and the use of artificial intelligence for the selection of embryos; assessments for endometrial receptivity and management of recurrent implantation failure; pre-implantation genetic testing (PGT) as a therapeutic tool opening up the possibility for aneuploidy screening; as well as the latest thoughts on nutritional health, periconception care, and the exciting new world of the microbiome.
Foreword
Richard S. Legro
Preface
About the Author
1. Epidemiology of Infertility, 21st-Century Considerations and the Covid-19 Pandemic
2. Prevention of Infertility
3. Planning a Pregnancy and Preconception Care
4. Obesity and Reproduction
5 Investigating Infertility
6. Anovulatory Infertility and Ovulation Induction
7. Polycystic Ovary Syndrome
8. Premature Ovarian Insufficiency and Oocyte Donation
9. Endometriosis
10. Tubal Infertility, Fibroids and Uterine Factors
11. Male Factor Infertility
12. Unexplained Infertility
13. Fertilisation
14. Fertility Preservation
15. Pre-Implantation Genetic Testing and Emerging Technologies
16. Complications of Ovarian Stimulation
17. Counselling and Modern Families
18. Ethical and Religious Issues
19. Health Outcomes of Children Born after Assisted Conception
20. Miscarriage and Ectopic Pregnancy
21. Recurrent Miscarriage and Recurrent Implantation Failure
22. Alternative Therapies and "Add-Ons"
23. When to Stop Treatment and Other Options
Appendix: Daily Vitamin and Mineral Requirements (See Chapter 3)
Books for Further Reading
Index
Biography
Adam Balen MB, BS, MD, DSc, FRCOG is a full time Consultant in Reproductive Medicine at Leeds Teaching Hospitals NHS Trust, Professor of Reproductive Medicine and Surgery at St. James’ University Hospital, Consultant and the Clinical Lead at Leeds Fertility, a partner at Balance Fertility, former Chair of the British Fertility Society, and the Royal College of Obstetricians and Gynaecologist's spokesperson for fertility.
