1st Edition
Injectable Drug Development Techniques to Reduce Pain and Irritation
472 Pages
by
CRC Press
Filled with strategies to minimize the adverse effects of injectable drugs, this book provides the scientific background and techniques required to evaluate parenteral formulations with respect to their potential to cause pain, irritation, and muscle damage. Using a unique, interdisciplinary approach, the book's editors and contributors represent the areas of pharmaceutics, physiology, anatomy,... Read more
o Challenges, M. Akers
o Pain, Irritation & Damage, W. Klement
o Muscle Damage with Injectables, A. McArdle & M. Jackson
o In Vitro Evaluation of Intravascular Hemolysis, J. Krzyzaniak &
S. Yalkowsky
o Lesion & Edema Models, S. Sutton
o Rat Paw-Lick Model, P. Gupta
o Radiopharmaceuticals for Noninvasive Evaluation, A. Feltus, M. Jay &
R. Beihn
o In Vitro & In Vivo Cytosolic Enzyme Release, G. Brazeau
o Histological & Morphological Methods, B. Carlson & R. Palmer
o Assessing Pain, J. Marcek
o Cosolvents in Injectables, S. Way & G. Brazeau
o Prodrugs, L. Prokai & K. Prokai-Tatrai
o Complexation-Cyclodextrins, M. Brewster & T. Loftsson
o Liposomal Formulations, F. Kadir, C. Oussoren & D. Crommelin
o Biodegradable Microparticles, E. Fattal, F. Quaglia, P. Gupta &
G. Brazeau
o Emulsions, P. Gupta & J. Cannon
o Minimizing Injection Pain & Damage, L. Gatlin & C. Gatlin
o Pain, Irritation & Damage, W. Klement
o Muscle Damage with Injectables, A. McArdle & M. Jackson
o In Vitro Evaluation of Intravascular Hemolysis, J. Krzyzaniak &
S. Yalkowsky
o Lesion & Edema Models, S. Sutton
o Rat Paw-Lick Model, P. Gupta
o Radiopharmaceuticals for Noninvasive Evaluation, A. Feltus, M. Jay &
R. Beihn
o In Vitro & In Vivo Cytosolic Enzyme Release, G. Brazeau
o Histological & Morphological Methods, B. Carlson & R. Palmer
o Assessing Pain, J. Marcek
o Cosolvents in Injectables, S. Way & G. Brazeau
o Prodrugs, L. Prokai & K. Prokai-Tatrai
o Complexation-Cyclodextrins, M. Brewster & T. Loftsson
o Liposomal Formulations, F. Kadir, C. Oussoren & D. Crommelin
o Biodegradable Microparticles, E. Fattal, F. Quaglia, P. Gupta &
G. Brazeau
o Emulsions, P. Gupta & J. Cannon
o Minimizing Injection Pain & Damage, L. Gatlin & C. Gatlin
Biography
Pramod K. Gupta, Gayle A. Brazeau
