Integrative Omics and Systems Pharmacology for COVID-19

1. An Overview of COVID-19: Highlighting the Impact of New Variants

Aqsa Majgaonkar, Dwaipayan Sinha, Zoofishan Kazi, Abhra Abir Chowdhury, Supti Das, Arun Kumar Maurya, and Nisha Bhat

2. Integrated Omics and Systems Pharmacology-Based Drug Discovery for COVID-19: An Overview

Kruthi Ashok Kumar, Rithika Shibu, Raunak Kumar Das, Ramya Shanmugam, Alagarsamy Sumitrha, Shanmugam Gavaskar, Shanmugam Velayuthaprabhu, and Arumugam Vijaya Anand

3. In Silico and Integrated Pharmacology Approaches for Developing Therapeutics for Treating Infectivity and Immunopathogenesis of SARS-CoV-2: An Overview

Atrayee Dey, Diptesh Goswami, Shubhranil Brahma, Ankita Chakraborty, and Suprabhat Mukherjee

4. Exploring Natural Compounds and Traditional Herbal Medicines as Anti-SARS-CoV-2 Agents: Insights into Molecular Mechanisms and Systems Pharmacology Approaches

Anand Kumar Pandey and Shalja Verma

5. Network Pharmacology of Natural Compounds and Traditional Herbal Medicines for COVID-19 Treatment

Arun Bahadur Gurung and Atanu Bhattacharjee

6. Multi-Omics and Network Pharmacology Approaches for Unraveling Druggable Targets of Natural Products in COVID-19 Treatment

Eman Shawky and Reham S. Ibrahim

7. Multi-Omics and Artificial Intelligence-Based Therapeutic Screening of Plant-Derived Bioactive Products Against the SARS-CoV-2 Infection

Muhammad Adil and Pragya Tiwari

8. Systems Pharmacology Approaches on the Anti-SARS-CoV-2 Activity of Natural Products

Samiksha Garse, Vaishnavi Thakur, Juhi Gupta, Shine Devarajan, Mustansir Bhori, Kanchanlata Tungare, and Sekar Vijayakumar

9. Multi-Omics Approaches in the Management of COVID-19: Drug Discovery and Diagnostic Strategies

Rania Hamdy, Ahmed M. Almehdi, Ihsan A. Shehadi, Kareem A. Mosa, Ismail Saadoun, Ali El-Keblawy, and Sameh S. M. Soliman

10. Omics Approaches for Anti-SARS-CoV-2 Drug Discovery

Sora Yasri and Viroj Wiwanitkit

11. Protein Targets for the Anti-SARS-CoV-2 Activity of Natural Compounds

Sora Yasri, and Viroj Wiwanitkit

12. Molecular Mechanisms of RNA-Dependent RNA Polymerase Inhibitors Against COVID-19 from Natural Compounds

Bancha Yingngam

13. Molecular Mechanisms of Proteases 3CLpro and PLpro Inhibitors Against COVID-19 from Natural Compounds and Traditional Herbal Medicines

Raghvendra Dubey and Kushagra Dubey

14. Molecular Mechanisms of Helicase Inhibitors Against COVID-19 from Natural Compounds

Karmakar Debprosit, Joshi Vedant, Tenguriya Kanishka, Verma Ravindra, and Kotnis Ashwin

15. Flavonoids: Anti-SARS-CoV-2 Activity Against Protein Targets Revealed by Network Pharmacology

Gunna Sureshbabu Suruthi, Ramesh Nivedha, Vishnu Puliyampatty Gunasekaran, Marudhachalam Kamalesh, Arthi Boro, Balasubramanian Balamuralikrishnan, Puzhakkal Abhirami, and Arumugam Vijaya Anand

16. Natural Compounds of Aquatic Plants Against SARS-CoV-2: The Mode of Action

Ahmed E. Alprol and Mohamed Ashour

17. Application of Artificial Intelligence on COVID-19 Management and Its Impact on Drug Discovery and Computational Medicine

Ramesh Nivedha, Gunna Sureshbabu Suruthi, Amardeep Preethi, Shanmugam Gavaskar, Alagarsamy Sumitrha, Puzhakkal Abhirami, Arthi Boro, and Arumugam Vijaya Anand

Biography

Jen-Tsung Chen, PhD, is a Professor of Cell Biology at the National University of Kaohsiung in Taiwan, where he teaches genomics, proteomics, plant physiology, and plant biotechnology. Dr. Chen’s research interests include bioactive compounds, chromatography techniques, plant molecular biology, plant biotechnology, bioinformatics, and systems pharmacology. He is an active editor of academic books and journals in an effort to advance the exploration of multidisciplinary knowledge involving plant physiology, plant biotechnology, nanotechnology, ethnopharmacology, systems biology, and drug discovery. He serves as an editorial board member and a guest editor for several reputed journals. Dr. Chen has published books in collaboration with international publishers on diverse topics such as drug discovery, herbal medicine, medicinal biotechnology, nanotechnology, bioengineering, plant functional genomics, plant speed breeding, CRISPR-based plant genome editing, and artificial intelligence. He has been included in the list of the World’s Top 2% Scientists 2023 by Stanford University.