2nd Edition
Introduction to Cell Mechanics and Mechanobiology
PART I Principles
1. Cell Mechanics as a Framework
2. Fundamentals in Cell Biology
3. Solid Mechanics Primer
4. Fluid Mechanics Primer
5. Statistical Mechanics Primer
6. Cell Mechanics in the Laboratory
PART II Practices
7. Mechanics of Cellular Polymers
8. Polymer Networks and the Cytoskeleton
9. Mechanics of the Cell Membrane
10. Adhesion, Migration, and Contraction
11. Cellular Mechanotransduction
12. Biomechanics and Mechanobiology of the Nucleus
Biography
Christopher R. Jacobs (1965–2018) was a Professor of Biomedical Engineering at Columbia University, where he served as the director of the Cell and Molecular Biomechanics Lab. A recognized leader in the field, Dr. Jacobs made seminal contributions to the understanding of bone cellular mechanotransduction and computational biomechanics, conducting research that aided in the development of new therapies for age-related bone loss and osteoporosis. His dedication to bridging the disciplines of mechanics and biology continues to influence the field.
Hayden Huang is a biomedical engineer by training. He currently works on issues at the intersection of health care and technology to help inform policymakers. Previously, he was a faculty member in the Department of Biomedical Engineering at Columbia University, where his research investigated cell mechanics and cardiovascular physiology. Dr. Huang was a key architect of the original Introduction to Cell Mechanics and Mechanobiology, drawing on his experience teaching the subject to a wide range of students from engineering to biological backgrounds.
Mohammad R. Kaazempur Mofrad is a Professor of Bioengineering and Mechanical Engineering at UC Berkeley, where he leads a multidisciplinary research program at the interface of biomechanics, mechanobiology, artificial intelligence, and computational biology. His laboratory investigates how physical forces shape biological structure and function across molecular, cellular, and multicellular scales, while also developing computational tools and AIdriven approaches to advance human health.
