6th Edition

Introduction to Nutrition and Metabolism

    452 Pages
    by CRC Press

    452 Pages
    by CRC Press

    Introduction to Nutrition and Metabolism equips readers with an understanding of the scientific basis of what we call a healthy diet. Now in its sixth edition, this highly recognized textbook provides clear explanations of how nutrients are metabolized and gives the principles of biochemistry needed for comprehending the science of nutrition.

    This full-color textbook explores the need for food and the uses to which food is put in the body, as well as the interactions between health and diet. Outlining the scientific basis behind nutritional requirements and recommendations, this new edition has been extensively revised to reflect current knowledge.

    Features:

    • Lists key objectives at the beginning, and summary points at the end of each chapter.
    • Accompanying online resources include interactive tutorial exercises based on interpretation of clinical and research data.
    • Covers topics including: Chemical reactions and catalysis by enzymes; the role of ATP; digestion and absorption of carbohydrates, fats and proteins; issues associated with being overweight; problems of malnutrition; diet and health; and vitamin and mineral requirements and functions.
    • Updated sections focus on the interaction of the gut microbiome and epigenetics with our metabolic responses to diet.
    • Provides a foundation of scientific knowledge for the interpretation and evaluation of future advances in nutrition and health sciences.

    Following its predecessors, this sixth edition is relevant to any student or practitioner interested in how diet influences our health, including in the fields of nutrition, dietetics, medicine and public health.

    Contents

    Preface .......................................................................................................................................... xvii

    Authors .......................................................................................................................................... xix

    Additional Resources on the Website: Metabolism Online – The Virtual Tutorial ........................ xxi

    Chapter 1 Why Eat? ..................................................................................................................... 1

    Chapter 2 Enzymes and Metabolic Pathways ...................................................................... 21

    Chapter 3 The Role of ATP in Metabolism .......................................................................... 53

    Chapter 4 Digestion and Absorption .................................................................................... 83

    Chapter 5 Energy Nutrition: The Metabolism of Carbohydrates and Fats .................. 121

    Chapter 6 Diet and Health: Nutrition and Chronic Noncommunicable Diseases …. 1 73

    Chapter 7 Overweight and Obesity ..................................................................................... 223

    Chapter 8 Protein- Energy Malnutrition: Problems of Undernutrition ......................... 247

    Chapter 9 Protein Nutrition and Metabolism ................................................................... 259

    Chapter 10 The Integration and Control of Metabolism ................................................... 293

    Chapter 11 Micronutrients: The Vitamins and Minerals .................................................. 323

    Index ............................................................................................................................................. 421

    Biography

    David A. Bender was educated at North Ealing Primary School and Greenford County

    Grammar School in London and then studied biochemistry at the University of Birmingham

    in England from 1965 to 1968. He joined the Courtauld Institute of Biochemistry at the

    Middlesex Hospital Medical School as a research assistant in 1968, was appointed as a

    lecturer in biochemistry in 1970 and received his PhD (on the metabolism of aromatic

    amino acids) from the University of London in 1971. The Middlesex Hospital Medical

    School merged with University College London (UCL) in 1987, and he became a member

    of the Department of Biochemistry and Molecular Biology at UCL. He was appointed as

    senior lecturer in biochemistry in 1994 and professor of nutritional biochemistry in 2009.

    He retired from UCL in 2011, with the title of Emeritus Professor. From 1994 until retirement,

    he was the assistant faculty tutor to the medical students, and from 1998 he was

    the subdean (Education) and director of studies for the early years of the medical course

    at UCL.

    His research interests have been in the fi eld of amino acid and vitamin nutritional

    biochemistry, and he was a member of the working group on vitamins that formed part of

    the expert committee that produced the 1991 report on Dietary Reference Values for Food

    Energy and Nutrients for the United Kingdom, the European Union expert committee that

    produced the 1993 report on Nutrient and Energy Intakes for the European Community

    and the Food Safety Authority of Ireland working party on Safe Micronutrient Levels.

    In addition to research publications, he has also written a number of books, including:

    Nutritional Biochemistry of the Vitamins , 2nd Edition, 2003, Cambridge University Press.

    Amino Acid Metabolism , 3rd Edition, 2012, Wiley- Blackwell.

    Benders’ Dictionary of Nutrition and Food Technology , 8th Edition, 2006, Woodhead

    Publishing, Oxford.

    Dictionary of Food and Nutrition , 3rd Edition, 2009, Oxford University Press.

    For more information about David A. Bender, visit http:// david- bender.co.uk.

    Shauna M. C. Cunningham was educated at Bank Street Primary School and Greenwood

    Academy in Irvine, Scotland, before undertaking undergraduate studies at Glasgow

    University. She moved to Aberdeen University in 1991 to study for a PhD. This was

    followed by a period of postdoctoral research at Aberdeen University and Kurume

    University Medical School, Japan, before she joined the Nutrition and Dietetics Teaching

    Group in 2001 as a lecturer in nutritional physiology and biochemistry at Robert Gordon

    University in Aberdeen. Shauna continues to teach student nutritionists and dietitians at

    Robert Gordon University, with a particular interest in metabolism and its relationship

    with diet.

    Amy Hess Fischl, MS RDN LDN BC-ADM CDCES(University of Chicago Medical Center)  **Description** This sixth edition of a primer of nutritional biochemistry, coming seven years after the last edition, builds on previous content to include key emerging areas of nutrition research, specifically the gut microbiome and epigenetics.*Purpose** The purpose is to enable readers to gain a working knowledge of how nutrients are metabolized and how they influence our metabolic status since these boiling blocks of knowledge are key to our relationship with food. Nutritional biochemistry is crucial to our understanding of the scientific basis behind eating principles. The book meets these objectives.**Audience** The book is written for "those using this information in their studies," which I consider to be nutrition students and nutrition practitioners. The book meets the needs of this audience. The lead author has been part of this book since the first edition. The second author also appears to be a credible authority as a nutrition lecturer and professor.**Features** The eleven chapters cover the key topics in nutritional biochemistry: micronutrients, enzymes and metabolic pathways, the role of ATP, digestion and absorption, metabolism of the macronutrients. The first chapter also delves into why we eat and spends a little time discussing religion, cultural differences, availability, and social status, which is a practical way to lay the framework for the information the book provides. The chapter on diet and health adds nutrition genomics to the conversation as well. While the book is laden with key content, the lead author also provides an additional resource on a website he controls called "The Virtual Tutorial." This has interactive exercises to help readers understand the metabolism of energy, carbohydrate, lipids, and protein. The author suggests that the exercises can be completed alone or in a group "gathered around the same computer." While the website is not formally part of the book, it does appear that it would be helpful for readers to test their knowledge in a more tangible way.**Assessment** This book is a perfectly acceptable option for students who are required to take a nutritional biochemistry course. Given the time between editions, this update is justified.--Weighted Numerical Score: 73 - 3 Stars