Introduction to Pharmacology: 3rd Edition (Paperback) book cover

Introduction to Pharmacology

3rd Edition

By Mannfred A. Hollinger

CRC Press

448 pages | 80 B/W Illus.

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Paperback: 9781420047417
pub: 2007-10-19
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Description

Advances in pharmacogenomics and proteomics, along with the introduction of recombinant DNA technology, have expanded the applications of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the development and delivery of novel drugs. Therefore, students in a variety of life sciences now require grounding in pharmacology.

Adding much new material, Introduction to Pharmacology, Third Edition familiarizes students with the curative action of specific drugs, along with current research and the multifaceted role of pharmacology in society.

New to the third edition—

· Chapters on smooth muscle pharmacology covering gastrointestinal and pulmonary pharmacology

· Pharmacology advances at the molecular level

· The historical background of the Watson Crick model of DNA

· Cutting edge topics such as RNA interference and dopamine signaling

The text begins with a discussion on the absorption, distribution, metabolism, and elimination of drugs. Much emphasis is placed on pharmacokinetic aspects: how drugs produce an effect and the quantification of these effects for comparative purposes. Also the text describes substance abuse pharmacology and the evolution of drug laws. Several chapters deal with the development of drugs and challenges faced in drug discovery.

Identifying both the therapeutic and toxicological aspects of drug use, Introduction to Pharmacology employs contemporary examples to help students become familiar with drug development and treatment, as well as possible adverse affects, and the impact of drug research and use on society today and into the future.

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Table of Contents

PART I- FUNDAMENTALS OF PHARMACOKINETICS

Introduction

Absorption and Distribution

Metabolism and Elimination

Drug Interaction

PART II- FUNDAMENTALS OF PHARMACODYNAMICS AND TOXICODYNAMICS

Drug Receptors

Dose-Response Relationship

Drug Toxicity

Treating Drug Toxicity

PART III- DRUGS THAT REPLACE, CURE, OR TREAT SYMPTOMS

Hormones

Chemotherapeutic Agents: Antibiotics and Anticancer Drugs

Drug Treatment of Symptoms: Neuropharmacology and Substance Abuse

Cardiovascular Drugs

Pulmonary Pharmacology

Gastrointestinal Pharmacology

PART IV- DRUG DEVELOPMENT

Drug Discovery by the Pharmaceutical Industry

Pharmaceutical Development of Drugs and the FDA

Animals in Research

Alternative Medicine

PART V- APPENDICES, GLOSSARY, AND CALCULTIONS

Appendix I: The History of Drug Abuse Laws in the United States

Appendix II: Molecular Structure of Nucleic Acids

Appendix III: Glossary

Appendix IV: Top 10 Drugs in History

Appendix V: Answers to Self-Assessment Questions

Subject Categories

BISAC Subject Codes/Headings:
MED071000
MEDICAL / Pharmacology