INTRODUCTION
What is Mass?
Fragmentation
The Mass Spectrometer
sample Introduction
Ionization
Mass Separation
Resolution
Ion Detection
Data Presentation
ELECTRON IONIZATION
Ion Formation
Types of Ions
Molecular Ion
Fragment Ion
Multiply Charged Ion
Molecular Ions
Isotope Peaks
Group 1
Group 2
Group 3
Multiply Charged Ions
Neutral Fragments
Basic Mass Spectral Reactions
Introduction
Simple cleavage
Multicenter fragmentations
Expulsion of Stable Neutral Fragments
Interpreting EI Mass Spectra
ACCURATE MASS MEASUREMENT
Introduction
Mass Calibration
Elemental Compositions
Applications
MODERN TECHNIQUES
Introduction
Gas Chromatography-Mass Spectrometry
Introduction
Applications
Low Energy Ionization
Low Electron Energy
Field Ionization
Fast Atom Bombardment
Photoionization
Chemical Ionization
Electrospray Ionization
Atmospheric Pressure Chemical Ionization
Matrix-Assisted Laser Desorption Ionization
Direct Analysis in Real Time
Liquid Chromatography-Mass Spectrometry
Introduction
Applications
Appendix I Answers to Problems
Index
Biography
Stephen Shrader , founder of Shrader Analytical and Consulting Laboratories, was among the early third-generation mass spectroscopists, starting in 1963. He is an internationally recognized expert in the use of mass spectrometry for structural elucidation and resolution of chemical problems in the petroleum, pharmaceutical, environmental, and polymer fields. His work has included periods in academia, the pharmaceutical industry, and a long stint as a consultant to the overall chemical industry. Throughout his 40-plus-year career, he has shared his experiences and knowledge of mass spectrometry via numerous seminars and classes. He has also been instrumental in developing a set of software tools called TSS Unity for displaying, printing, and evaluating mass spectral data for the purpose of solving chemical problems.
