1st Edition

Invasomes as Drug Nanocarriers for Innovative Pharmaceutical Dosage Forms

By Nina Dragićević Copyright 2021
    222 Pages 40 B/W Illustrations
    by CRC Press

    This book details the novel nanocarriers named 'invasomes" and how they are used for dermal and transdermal drug delivery. The text describes their composition, usage of skin as a drug delivery route and liposomes as skin delivery systems. Included are reviewed studies revealing the importance of invasomes in this field.


    About the Author

    1. The skin as a drug delivery route
    2. Lipid-based vesicles (liposomes) as skin delivery systems
    3. Invasomes as drug nanocarriers for dermal and transdermal drug delivery



    Dr. Nina Dragićević is a professor in Pharmaceutical technology at the Department of Pharmacy at the Singidunum University in Belgrade, Serbia. She earned her master’s degree at the University of Belgrade, Faculty of Pharmacy, in 1999 and subsequently earned a Magister Degree and a PhD (summa cum laude, Dr. rer. nat.) in Pharmaceutical technology from the University of Belgrade and the Friedrich-Schiller University Jena, Germany, respectively. Before her employment at the University Singidunum, Dr. Dragićević worked as an accredited specialist in Pharmaceutical technology in the state pharmaceutical chain Apoteka "Beograd" in Belgrade. From 2007 to 2013 she was responsible for the preparation of compounded drugs for different routes of administration in pharmacies of Apoteka "Beograd", and in 2013 she was appointed director of the Production Department in the same company. She has published in a variety of international journals and she is editor of six books.

    Over the last three decades, vesicular phospholipid nanocarriers have been used successfully as tools to improve dermal and transdermal drug delivery as well as in the cosmetic field. The most common nanocarriers used for skin delivery are liposomes. However, since they have failed in efficiently delivering drugs across the intact skin, intensive research has been devoted to the development of new lipid vesicles that are capable of improving this process.
    Invasomes represent a new class of vesicles, developed by introducing a mixture of terpenes and ethanol to the classic composition of liposomes, which have shown interesting results both in dermal and transdermal drug delivery.

    The book “Invasomes as Drug Nanocarriers for Innovative Pharmaceutical Dosage Forms “ provides a comprehensive source of information for researchers from both academia and industry.
    The first chapter deals the skin as a drug delivery route while the next chapter is a comprehensive overview on vesicular phospholipid nanocarriers. Then, the book content deals with preparation, characterization and evaluation of Invasomes, properly designed for delivering drugs and cosmetic active to the skin.

    Overall, the book provides readers with comprehensive knowledge about these nanocarriers, since the author of the book is one of the main researchers in the field of Invasomes.

    - Professor Chiara Sinico, University of Cagliari-Italy