1st Edition

Investigations in Yeast Functional Genomics and Molecular Biology

Edited By Matthew Eckwahl Copyright 2014
    412 Pages 73 B/W Illustrations
    by Apple Academic Press

    412 Pages 73 B/W Illustrations
    by Apple Academic Press

    This title includes a number of Open Access chapters.

    This book examines conserved pathways mediating cell cycle progression and cell polarity establishment. It includes examples of yeast, regulatory circuits, and feedback regulation, with emphasis on system-wide approaches. It also covers protein interaction networks and trait locus analysis and presents methods and challenges in comparative genomics analysis and evolutionary genetics.

    Cell Polarity, Growth, and Cell Cycle
    Daughter-Specific Transcription Factors Regulate Cell Size Control in Budding Yeast, Stefano Di Talia, Hongyin Wang, Jan M. Skotheim, Adam P. Rosebrock, Bruce Futcher, and Frederick R. Cross
    Modeling Robustness Tradeoffs in Yeast Cell Polarization Induced by Spatial Gradients, Ching-Shan Chou, Qing Nie, and Tau-Mu Yi
    Multisite Phosphorylation of the Guanine Nucleotide Exchange Factor Cdc24 during Yeast Cell Polarization, Stephanie C. Wai, Scott A. Gerber, and Rong Li

    Yeast Regulatory Circuits
    Roles of Candida albicans Gat2, a GATA-Type Zinc Finger Transcription Factor, in Biofilm Formation, Filamentous Growth and Virulence, Han Du, Guobo Guan, Jing Xie, Yuan Sun, Yaojun Tong, Lixin Zhang, and Guanghua Huang
    Deciphering Human Heat Shock Transcription Factor 1 Regulation via Post-Translational Modification in Yeast, Liliana Batista-Nascimento, Daniel W. Neef, Phillip C. C. Liu, Claudina Rodrigues-Pousada, and Dennis J. Thiele
    Environmental Regulation of Prions in Yeast, Liming Li and Anthony S. Kowal
    Heterologous Gln/Asn-Rich Proteins Impede the Propagation of Yeast Prions by Altering Chaperone Availability, Zi Yang, Joo Y. Hong, Irina L. Derkatch, and Susan W. Liebman

    Gene Expression and Trait Locus Analysis
    Strategy of Transcription Regulation in the Budding Yeast, Sagi Levy, Jan Ihmels, Miri Carmi, Adina Weinberger, Gilgi Friedlander, and Naama Barkai
    A Screen for RNA-Binding Proteins in Yeast Indicates Dual Functions for Many Enzymes, Tanja Scherrer, Nitish Mittal, Sarath Chandra Janga, and André P. Gerber
    Genetic Landscape of Open Chromatin in Yeast, Kibaick Lee, Sang Cheol Kim, Inkyung Jung, Kwoneel Kim, Jungmin Seo, Heun-Sik Lee, Gireesh K. Bogu, Dongsup Kim, Sanghyuk Lee, Byungwook Lee, and Jung Kyoon Choi

    Comparative Genomics
    High Quality de novo Sequencing and Assembly of the Saccharomyces arboricolus Genome, Gianni Liti, Alex N. Nguyen Ba, Martin Blythe, Carolin A. Müller, Anders Bergström, Francisco A. Cubillos, Felix Dafhnis-Calas, Shima Khoshraftar, Sunir Malla, Neel Mehta, Cheuk C. Siow, Jonas Warringer, Alan M. Moses, Edward J. Louis, and Conrad A. Nieduszynski
    Comparative Gene Expression Between Two Yeast Species, Yuanfang Guan, Maitreya J. Dunham, Olga G. Troyanskaya, and Amy A. Caudy
    Whole-Genome Comparison Reveals Novel Genetic Elements That Characterize the Genome of Industrial Strains of Saccharomyces cerevisiae, Anthony R. Borneman, Brian A. Desany, David Riches, Jason P. Affourtit, Angus H. Forgan, Isak S. Pretorius, Michael Egholm, and Paul J. Chambers


    Matthew Eckwahl is a graduate student at Yale University in the Department of Cell Biology, New Haven, Connecticut. He received his BS in molecular biology and biotechnology at the University of Michigan-Flint. Mr. Eckwahl has research experience in regulatory networks of psuedohyphal growth response and is currently working on the packaging of non-coding RNA by retroviruses.