832 pages | 165 B/W Illus.
This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and characterized in pulmonary artery smooth muscle, as well as a practical discussion of experimental tools for the study of ion channel physiology and molecular biology.
Cell Physiology. Ca2+-permeable Channels. Na+-permeable Channels. K+-permeable channels. Cl--permeable Channels. O2-sensitive Ion Channels. Water Channels (Aquaporins). Functional roles of Cytoplasmic Ions and Ion Channels. Role of Ion Channels In Pulmonary Vascular Diseases. Methodological Approaches