234 pages | 13 Color Illus. | 30 B/W Illus.
Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally, the book discusses clinical implications of acute and chronic renal toxicity.
Cellular Organelle-based Renal Toxicity
Molecular Modeling – Molecular Design
Systems Biological Approaches
Clinical Implication of Renal Toxicology
Molecular Pathology of Renal Fibrosis
Classification of Nephrotoxicants