1st Edition

Kidney Toxicological Assessment

Edited By Sang Geon Kim Copyright 2013
    234 Pages 13 Color & 30 B/W Illustrations
    by CRC Press

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    This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

    Section I
    Cellular Organelle-based Renal Toxicity
    Section II
    Transcriptomic Approaches
    Proteomic Approaches
    Metabolomic Approaches
    Section III
    Molecular Modeling – Molecular Design
    Systems Biological Approaches
    Virtual Cell
    Section IV
    Clinical Implication of Renal Toxicology
    Molecular Pathology of Renal Fibrosis
    Section V
    Classification of Nephrotoxicants


    Kim, Sang Geon