1st Edition
Lipid-Based Drug Delivery Systems Principles and Applications
This book appraises the role of lipid-based drug delivery systems (LBDDSs) with respect to the bioavailability and controlled delivery of complex drug molecules for improving their clinical viability. It covers the latest developments and advancements in the field of drug delivery, and explores and compiles information on the current situation of lipid-based formulations used as versatile excipients and all their possible routes to improve therapeutic benefits. The book discusses novel formulations such as depot formulations, micro- and nanoemulsions, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, nanoliposomes, micelles, nanosuspensions, lipid implants and inserts, and lipid nanotubes. It presents preparation methods of LBDDSs and their physicochemical properties, and portrays their various application angles and their impacts on drug-conveyance frameworks when employed in vitro and in vivo. The book is beneficial for researchers working on lipid-based drug formulations as well as biological and translational drug delivery. It is also a useful resource for course work of students of various academic degree programs such as pharmacy, health sciences, biotechnology, and microbiology; postgraduate and PhD students; and postdoctoral fellows researching on nanomedicine-based drug delivery systems.
1. Lipid-Based Excipients: The Holy Grail in Pharmaceutical Product Development
2. Solid Lipid Nanoparticles
3. Liposomal Drug Delivery Systems: Concept and Recent Advances in Clinical Applications
4. Lipid-Based Drug Delivery System: Spotlight on Nanoemulsion as Versatile Nanocarrier
5. Lipid Nanocrystals: An Overview on Formulation to Clinical Translation
6. Cubosomes
7. Transfersomes as Transporters via Lipid-Based Drug Delivery System
8. Ethosomes: A Lipid-Based Drug Delivery System
9. Dendrimers: A Lipid-Based Drug Delivery System
10. Microbubbles
11. Phytosome and Herbosome: A Vesicular Drug Delivery System for Improving the Bioavailability of Natural Products
12. Role of Lipids in Depot Injectables
13. Role of Lipids in Vaccine Drug Delivery
14. Lipid-Based Drug Delivery in Cancer
15. Targeting Brain Using Lipid-Based Formulations
16. Role of Lipids in Ocular Drug Delivery Systems
17. Role of Lipids in Pulmonary Drug Delivery Systems
18. Food and Nutraceuticals
19. Role of Lipids in Cosmeceuticals
20. Regulatory Status of Lipids for Pharmaceuticals and Cosmeceuticals
Biography
Bhupendra Prajapati is a professor at the Department of Pharmaceutics, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India. Dr Prajapati has more than 20 years of academic and research experience. He has published 120 research papers, edited 10 books, and authored 38 book chapters. His research focuses on modified and novel drug delivery. His h-index and i10-index are 22 and 39, respectively, with more than 1800 citations.
Jayvadan Patel is a formulation scientist at Aavis Pharmaceuticals, USA, and professor emeritus at the Faculty of Pharmacy, Sankalchand Patel University, India. Dr Patel has more than 26 years of experience in academics, research, and industry. He has published 270 research papers, co-authored 20 books, and contributed 122 book chapters. His papers have been cited more than 5600 times, and his h-index is 37 and i10-index is 126.
