1st Edition
Lipid Oxidation in Health and Disease
An Introduction to Redox Balance and Lipid Oxidation
Corinne M. Spickett, Maria Fedorova, Ralf Hoffmann, and Henry Jay Forman
CHEMISTRY AND BIOCHEMISTRY OF LIPID OXIDATION
Nonenzymatic Mechanisms of Lipid Oxidation
Claus Schneider and Sean S. Davies
Enzymatic Oxidation of Polyunsaturated Fatty Acids
Sharon A. Murphy, Naser M. I. Al-Aaswad, and Anna Nicolaou
Halogenated Lipids: Products of Peroxidase-Derived Reactive Halogenating Species Targeting Conventional Lipids
David A. Ford
Formation of Nitrated Lipids and Their Biological Relevance
Andrés Trostchansky and Homero Rubbo
Protein Lipoxidation
Koji Uchida
Analysis of Lipid Peroxidation Products in Health and Disease
Michael J. Thomas
SITES OF BIOLOGICAL ACTIONS OF OXIDIZED LIPIDS
Oxidized Lipids as Damage-Associated Molecular Patterns in Inflammatory Responses
Maria Fedorova and Ralf Hoffmann
Formation and Beneficial Roles of Polyunsaturated Lipid Mediators: Lipoxins, Resolvins, Protectins, and Maresins
Nicos A. Petasis
Pro- and Anti-Inflammatory Action of Oxidized Phospholipids
Maria Philippova, Olga Oskolkova, and Valery N. Bochkov
Modulation of Toll-Like Receptor Signaling by Oxidized Phospholipids
Vlad Serbulea and Norbert Leitinger
Dietary Oxidized Lipids as Regulators of Intracellular Signaling Pathways: PPAR and NF-KB
Robert Ringseis, Denise K. Gessner, and Klaus Eder
Oxidized and Nitrated Lipid Interactions with the Keap1-Nrf2 Pathway
Emilia Kansanen and Anna-Liisa Levonen
OXIDIZED LIPIDS IN PATHOLOGY AND DISEASE
Role of Oxidized Phospholipids in Cardiovascular Disease
Gregor Leibundgut, Adam Taleb, and Sotirios Tsimikas
Cholesterol Oxidation Products in the Initiation, Progression, and Fate of Atherosclerotic Lesions
Giuseppe Poli, Simona Gargiulo, Paola Gamba, Barbara Sottero, Fiorella Biasi, and Gabriella Leonarduzzi
Lipid Peroxidation and Age-Related Neurodegenerative Disorders
Tanea T. Reed, Zachariah P. Sellers, and D. Allan Butterfield
Association of Oxidative Stress and Lipids with Risk Factors of Metabolic Syndrome
Sampath Parthasarathy, Chandrakala Aluganti Narasimhulu, Irene Fernandez Ruiz, Kathryn Young, Vivek Krishna Pulakazhi Venu, Xueting Jiang, and Aladdin Riad
Oxidized Lipid Products and Carcinogenesis
Françoise Guéraud
Biography
Corinne M. Spickett is a reader at Aston University in Birmingham, UK. She has studied the analysis of phospholipid oxidation by electrospray mass spectrometry and the biological effects of oxidized lipids. More recently, she expanded her research to include analysis of protein oxidation and formation of lipoxidation products during inflammation, and has been developing label-free, semi-targeted approaches to their identification in biological samples.
Henry Jay Forman is a distinguished professor of biochemistry and chemistry and founding faculty at the University of California, Merced. His expertise is in the areas of oxidative stress and signal transduction. His major research achievements are pioneering work in mitochondrial superoxide production, redox signaling, and mechanisms of induced resistance to oxidative stress.
