324 pages | 121 B/W Illus.
Liposome Technology, Volume I: Liposome Preparation and Related Techniques, Third Edition, is a thoroughly updated and expanded new edition of a classic text in the field. Including step-by-step technical details, Volume I illustrates numerous methods for liposome preparation and auxiliary techniques necessary for the stabilization and characterization of liposomes. This source also offers critical discussions of the methodologies of each technology described so that readers can examine the benefits and limitations and compare it to other approaches.
Formation and Properties of Fatty Acid Vesicles (Liposomes). Formation and Physicochemical Properties of Lipid Vesicles (Liposomes) by the Coacervation Method. Preparation of Liposomes and Oily Formulations by Freeze-Drying Monophase Solutions. Formation of Large Unilamellar Vesicles by Extrusion. Preparation of Liposomes for Pulmonary Delivery Using Medical Nebulizers. Immunopotentiating Reconstituted Influenza Virosomes. Lipoplexes in Gene Therapy under the Considerations of Scaling Up, Stability Issues and Pharmaceutical Requirements. Synthesis and Advantages of Acid-Labile Formulations for Lipoplexes. Bioresponsive Lipids and Their Use for Macromolecular Delivery. Polymeric Vesicles Based on Hydrophilic Polymers Bearing Hydrophobic Pendant Groups. Mixed Vesicles and Mixed Micelles: Formation, Thermodynamic Stability and Pharmaceutical Aspects. Vesicular Phospholipid Gels. Stabilization of Liposomes by Freeze-Drying: Lessons from Nature. Hydrolysis of Phospholipids in Liposomes and Stability Indicating Analytical Techniques. Process Development and Quality Control of Injectable Liposomal Therapeutics.