Although the role of liposomes in drug targeting has been discussed extensively in several reviews and books, there has been no comprehensive coverage of related methodology. This book constitutes the first attempt to put together all aspects of lipsome technology as applied to medical sciences. Volume II describes procedures for the entrapment of a number of drugs, including genetic material, into selected types of lipsomes.
1. Model Studies for Drug Entrapment and Lipsome Stability 2. Preparation of Lipsomes Entrapping Cancer Chemotherapeutic Agents for Experimental In Vivo and In Vitro Studies 3. Liposome Encapsulation of Biological Response Modifiers: Activation of Tumoricidal Macrophages 4. Preparation of Liposomes for Use as Drug Carriers in the Treatment of Leishmaniasis 5. Incorporation of Factor VIII into Liposomes 6. Acetyl Glyceryl Ether Containing Liposomes 7. The Labeling of Liposomal Membranes with Radioactive Technetium 8. Methodological Considerations for the Use of Liposomes in Diagnostic Imaging 9. Liposomes and Carriers of Immunogenic Determinants 10. Incorporation of Membrane Proteins in Liposomes and their Use in immunoassay 11. Theoretical and Practical Consideration in Preparing Lipsomes for the Purpose of releasing Drug in Response to Changes in Temperature and pH 12. Experimental Procedures with Liposomes to Insert Macromolecules and Macromolecular Complexes into Muscle Cells in Culture 13. Entrapment of Genetic Material into Liposomes and Delivery to Cells 14. Entrapment of Genetic Materials into Liposomes and their Delivery to Plant Protoplasts 15. Entrapment of Recombinant DNA in Liposomes and its Transfer and Expression in Eukaryotic Cells