30th Edition

Litt's Drug Eruption & Reaction Manual

Edited By Neil H. Shear Copyright 2024
    530 Pages
    by CRC Press

    530 Pages
    by CRC Press

    Litt’s Drug Eruption & Reaction Manual is a succinct reference to give clinicians the essential information for an informed decision about patient management. The full database from which it is derived — Litt’s Drug Eruption & Reaction database: www.drugeruptiondata.com — currently holds over 1800 drug profiles with over 73,000 documented drug reactions, as evidenced by well over 156,000 references on PubMed, and is internationally relied upon by medical practitioners for its unparalleled focus on adverse effects and cutaneous reactions.

    As a special offer for this 30th edition, a 12-month free access to the database is offered to buyers of a new print copy of this edition in 2024.

    This edition:

    • Provides documentation of adverse reactions to the 1500 most consulted drug and herbal profiles
    • Gives clinicians managing patients with many different medications a route to making an informed decision about problematic reactions
    • Offers clinicians a one-stop reference for the essential information about a drug


    • A to Z listing of the 1500 most consulted drug and herbal profiles (including supplements, vaccines, and botanicals), including generic name and trade names; pharmaceutical company; indications; half-life; and pregnancy category
    • Descriptions of important reactions
    • List of drugs that cause important adverse reactions
    • List of main classes of drugs
    • 28 tables showing reactions of members of a class of drugs (such as statins or monoclonal antibodies), enabling clinicians to see at a glance whether a reaction is common to all drugs included in that class, or to a majority of them, or is known in only a handful—information that is critical for an informed decision to change drugs within the same class
    • 2 tables showing reported genetic associations with cutaneous adverse drug reactions and recommendations regarding genetic screening to prevent cutaneous adverse drug reactions
    • A concordance of synonyms and trade names for ease of cross-reference

    Introductory note

    Drug profiles: generic names A–Z

    Descriptions of important reactions

    Drugs that cause important reactions

    Main classes of drugs

    Class reactions

    ACE inhibitors. Antiarrhythmics. Antibiotics, macrolide. Anticonvulsants. Antidepressants, tricyclic. Antifungal, Imidazole. Antimalarials. Antineoplastics. Antipsychotics. Antiretrovirals. Benzodiazepines. Beta blockers. Bisphosphonates. Calcium channel blockers. Cephalosporins. Corticosteroids, topical. Dipeptidyl-Peptidase 4 (DPP4) inhibitors. Disease-modifying antirheumatic drugs (DMARDS). Epidermal growth factor receptor (EGFR) inhibitors. Fluoroquinolones. H1 receptor antagonists. HMG-CoA reductase inhibitors/statins. Immune checkpoint inhibitors. Monoclonal antibodies. Non-steroidal anti-inflammatories (NSAIDS). Proton pump inhibitors (PPI). TNF inhibitors. Tyrosine-kinase inhibitors.

    Genetic associations

    Concordance of synonyms and trade names with generic names


    Neil H. Shear, MD, FRCPC, FACP is Professor of Dermatology and Clinical Pharmacology and Toxicology, University of Toronto, Canada.