These volumes represent the "state-of-the-art" in morphological methods for detection of steroid receptors. In Volume I we have attempted to collect current available methods and experimental approahes which might be useful in solving present enigmas. The background and recent advances presented are intended to stimulate further experimentation and new innovations, and spur clinical trials by all investigators with an interest in steroid hormones, cell biology, and clinical oncology.
Table of Contents
1. An overview 2. Radioautographic Localization of Estrogen Receptors in the Rat Uterus: a Tool for the Study of Classical and Nontraditional Mechanisms of Hormone Action 3. Fluoresceinated Estrone Binding by Normal and Neoplastic Cells of Human and Animal Origin 4. Histochemical Study of Estrogen Receptors in the Rat Uterus With a Hydrophilic Fluorescent Estradiol Conjugate 5. Estrogen Receptors and Hormone Responsiveness in Serially Transplanted Mammary Tumors in Rats 6. Flow Cytometric Analysis of Fluorescent Estrogen Binding in Cancer Cell Suspensions 7. Sex Steroid Action Mechanism by Cytochemistry in Normal and Neoplastic Target Tissues 8. Immunohistochemical Studies with Antibodies to the Chicken Oviduct Progesterone Receptor 9. Methods for the Quantification of Histochemical Steroid Binding Assays 10. A Two-State Immunocytochemical Method for Putative Estrogen Receptor Analysis 11. Estradiol-BSA Conjugates for Estrogen Receptor Localization: the Vienna Experience