1st Edition

Lysosomal Pathways of Protein Degradation

By J Fred Dice Copyright 2000
106 Pages 60 B/W Illustrations
by CRC Press

106 Pages
by CRC Press

Lysosomal Pathways of Protein Degradation looks at cell biology from the view of a lysosome. It summarizes the composition and assembly of lysosomes in mammalian and yeast cells. It also reviews current knowledge about pathways of endocytosis and secretion and how both endocytosed and secreted proteins can be delivered to lysosomes for degradation. In addition, both vesicular and nonvesicular... Read more
1. Introduction, Methods Used to Study Lysosomes, Terminology, Acidification of Lysosomes, Biogenesis of Mammalian Lysosomes, Biogenesis of the Yeast Vacuole, Degradation of Lysosomal Proteins, Future Directions of Research 2 Degradation of Endocytosed and Plasma Membrane Proteins 3 Lysosomal Degradation of Proteins in the Secretory 4. Degradation of Intracellular Proteins by Macroautophagy 5. Degradation of Intracellular Protein by Microautophagy 6. Selective Pathway for Degradation of Cystolic Proteins by Lysosomes 7. Concluding Remark

Biography

J Fred Dice, Department of Physiology Tufts University School of Medicine Boston, Massachusetts, U.S.A.