7th Edition
McDonald’s Blood Flow in Arteries Theoretical, Experimental and Clinical Principles
Foreword to the First Edition
Preface
About the Authors
List of Contributors
Abbreviations and Acronyms
Glossary of Terms
1. Introduction
Michael O’Rourke, Audrey Adji
2. Anatomy of the Heart and Circulation
Elazer Edelman, Farhad Rikhtegar Nezami
3. Nature of Flow of a Liquid
Wilmer Nichols
4. Properties of the Arterial Wall: Theory and Practice
Wilmer Nichols
5. Endothelial Cells and Hemodynamics
Elazer Edelman, Farhad Rikhtegar Nezami
6. General Principles for Measuring Arterial Waves
Wilmer Nichols
7. Pulsatile Pressure–Flow Relations
Wilmer Nichols
8. Arterial Wave Refl ections
Michael O’Rourke, Audrey Adji
9. Contour of Pressure and Flow Waves in Arteries
Michael O’Rourke, Audrey Adji
10. Principles of Recording and Analysis of Arterial Waveforms
Wilmer Nichols
11. Vascular Impedance
Michael O’Rourke, Audrey Adji
12. Coupling of the Left Ventricle with the Systemic Circulation: Implications to Cardiac Failure
Michael O’Rourke, Audrey Adji
13. Pulmonary Circulation
Michael O’Rourke, Audrey Adji
14. Specialized Circulations in Susceptible Tissues
Michael O’Rourke, Audrey Adji
15. Aging, Growth and Maturation
Michael O’Rourke, Audrey Adji
16. Hypertension
Michael O’Rourke, Audrey Adji
17. Interpretation of Blood Pressure in Epidemiological Studies and Clinical Trials
Michael O’Rourke, Audrey Adji
18. Arterial Biomarkers
Charalambos Vlachopoulos
19. Arteriosclerosis and Atherosclerosis: Clinical Issues
Michael O’Rourke
20. Specifi c Arterial Disease
Charalambos Vlachopoulos
21. Generalized and Metabolic Disease
Charalambos Vlachopoulos
22. Emergence of Therapeutic Strategies
Michael O’Rourke, Audrey Adji
23. Endovascular Implants
Elazer Edelman, Lambros Athanasiou, Farhad Rikhtegar Nezami
24. Cardiovascular Effects of Exercise
Wilmer Nichols
25. Central Arterial Pressure
Charalambos Vlachopoulos and Michael O’Rourke, Audrey Adji
26. Lifestyle and Environment
Charalambos Vlachopoulos
27. Arterial Pressure Waveform Analysis
Michael O’Rourke, Audrey Adji
Bibliography
Index
Biography
Dr. Wilmer Nichols, PhD., is Emeritus Professor of Cardiovascular Medicine in the School of Medicine at the University of Florida in Gainesville, Florida. His career has been dedicated to the investigation of structure and function of the heart and arterial system in age and arterial disease. He has published over 200 articles in peer reviewed journals; books include the 6th edition of McDonald’s Blood Flow in Arteries. Among his many awards are Lifetime Achievement Awards from the Artery Society of Europe and the North American Artery Society.
Dr. Michael O’Rourke, MD, DSc., is Professor of Medicine (Emeritus) at the University of New South Wales (UNSW) and a Cardiologist at St. Vincent’s Hospital, Sydney. His basic research training was in arterial hemodynamics, working on experimental animals and computer models with Michael Taylor (Sydney) and William Milnor (Baltimore). He has published over 500 articles in peer reviewed journals; books include the 6th edition (2011) of McDonald’s Blood Flow in Arteries. Recent research is into cardiovascular aging, using new methods of pulse waveform analysis to detect, explain and treat ill-effects on the heart and brain from midlife in asymptomatic subjects.
Dr. Elazer Edelman, MD, PhD., is the Edward J. Poitras Professor in Medical Engineering and Science at Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts where he directs the Institute of Medical Engineering and Science. He is also Professor of Medicine at Harvard Medical School, and a cardiac intensive care unit cardiologist at the Brigham and Women’s Hospital in Boston.
Dr. Charalambos Vlachopoulos MD is Professor of Cardiology at the 1st Department of Cardiology, Hippokration Hospital, University of Athens Medical School with clinical interests in hypertension and interventional cardiology. Professor Vlachopoulos is currently Chairman of the European Society of Cardiology Working Group "Peripheral Circulation" and President of the Artery Society. Together with Wilmer Nichols and Michael O’Rourke he has authored the 6th Edition of "McDonald’s Blood Flow in Arteries". He has lectured extensively in international conferences. He is a member of the Board of Hypertension, Artery Research, and Hellenic Journal of Cardiology and a Reviewer for numerous Medical Journals.
This book is informationally sound with exquisite detail and focus on the physics of the cardiovascular system.
- Kara E Gilliam, BA, MD/MPH Candidate, East Tennessee State University Quillen
College of Medicine
