Mechanobiology of the Endothelium: 1st Edition (Hardback) book cover

Mechanobiology of the Endothelium

1st Edition

Edited by Helim Aranda-Espinoza

CRC Press

280 pages | 23 Color Illus. | 20 B/W Illus.

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Hardback: 9781482207248
pub: 2015-02-25
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The endothelium is an excellent example of where biology meets physics and engineering. It must convert mechanical forces into chemical signals to maintain homeostasis. It also controls the immune response, drug delivery through the vasculature, and cancer metastasis. Basic understanding of these processes is starting to emerge and the knowledge gained from research is now being used in applications from drug delivery to imaging modalities. This book reviews current knowledge in mechanobiology of the endothelium and its implications for the development of theranostic devices.

Table of Contents

The Endothelium as a Mechanosensor

Rachel E. Neubrander and Brian P. Helmke

Mechanobiology of the Endothelial Nucleus

Elizabeth A. Booth-Gauthier, Stephen Spagnol, Kris Noel Dahl

Cancer Metastasis and Biomechanics of the Endothelium

Claudia T. Mierke

Valvular Endothelial Mechanobiology

Suthan Srigunapalan and Craig A. Simmons

Environmental Factors that Influence the Response of the Endothelium to Flow

Tracy M. Cheung and George A. Truskey

Differential Response of the Endothelium to Simultaneous Chemical and Mechanical Stimulation in Inflammation Response

Ryan B. Huang and Omolola Eniola-Adefeso

The Role of Cholesterol and Lipoproteins in Control of Endothelial Biomechanics

Irena Levitan, Tzu-Pin Shentu, Mingzhai Sun, and Gabor Forgacs

Implications of Fluid Shear Stress in Capillary Sprouting during Adult Microvascular Network Remodeling

Walter L. Murfee

Endothelial Cell Adhesion Molecules and Drug Delivery Applications

Daniel Serrano and Silvia Muro

Leukocyte Transendothelial Migration: A Biophysical Event

Kimberly M. Stroka

The Immune System as a Theranostic Device

Janina A. Vaitkus and Helim Aranda-Espinoza

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Anatomy
MEDICAL / Biotechnology
MEDICAL / Cardiology
MEDICAL / Pharmacy
SCIENCE / Life Sciences / Cytology