1st Edition

Medical Cytogenetics

ISBN 9780824719999
Published April 11, 2000 by CRC Press
728 Pages

USD $180.00

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Book Description

The only monograph on cytogenetics for the pathologist, this up-to-the-minute reference/text contains the most up-to-date research findings on many important topics in medical genetics-notably FISH (fluorescent in situ hybridation)-based molecular cytogenetic technologies and spectral karyotyping.
An excellent resource for cytogeneticists preparing for the certifying examination in Clinical Cytogenetics offered by the American Board of Medical Genetics (ABMG).
Written by nearly 30 distinguished international contributors, Medical Cytogenetics

  • covers the history of the field, tissue culturing and staining techniques, and clinical applications of FISH, as well as other methods for genetic studies and chromosomal analysis
  • supplies numerous examples and case reports
  • examines reproductive dysfunctions such as in-utero abnormalities, male infertility, and failure to conceive
  • investigates chromosomal abnormalities associated with myeloid hematopoietic disorders, lymphoid neoplasms, and solid tumors such as those associated with breast cancer
  • reviews means of obtaining accreditation or licenses, use of external peer reviews and voluntary inspections, proficiency testing, and regulatory oversight
  • and more!
    Thoroughly referenced with over 1800 bibliographic citations, and supplemented with a useful glossary, a large number of practice questions, and over 40 color photographs, Medical Cytogenetics is a pragmatic, hands-on reference for pathologists, geneticists, cytogenetic technologists, molecular and cell biologists, clinical and medical oncologists, hematologists, neurologists, pediatricians, endocrinologists, obstetricians, gynecologists, and primary care physicians, and an exceptional text for upper-level undergraduate, graduate, and medical students in these disciplines.
  • Reviews

    Prepublication praise for Medical Cytogenetics…

    …a very unique resource. Currently, there is no cytogenetics book that is targeted for pathologists….this book will fill this void.
    The authors…have succeeded in conveying the excitement of this rapidly evolving field….The book is filled with many practical examples and illustrations.
    "-Julius M. Cruse,
    Editor-in-Chief, Experimental and Molecular Pathology, and Professor of Pathology, Director of Immunopathology and Transplantation Immunology, Department of Pathology, School of Medicine, The University of Mississippi Medical Center, Jackson

    "…presents an insightful overview of the scientific, technical, medical, institutional, educational and regulatory influences that have been responsible for the exponential growth and increasing sophistication of this discipline….
    Because of its breadth, clarity, and state-of-the-art message, this volume will serve as an excellent resource both for experienced medical cytogeneticists and trainees new to the discipline….highly recommended.
    "-Sudarshan K. Malhotra, Professor Emeritus of Biological Sciences, University of Alberta, Canada, and Theodor K. Shnitka, Professor Emeritus of Pathology, University of Alberta, Canada

    "…excellent, impressive, long overdue, concise, and comprehensive….a highly recommended addition to institutional and personal libraries.
    "-Ernest M. Walker, Jr., Department of Pathology, Marshall University School of Medicine, Huntington, West Virginia

    "…This book…provides a thorough and clear starting point for students new to cytogenetics. At the same time, it provides a complete coverage of the many applications cytogenetics has come to play currently in medicine….
    …an excellent resource.
    "-from the Foreword by Thaddeus E. Kelly, Professor of Pediatrics, Director, Division of Medical Genetics, Children's Medical Center, University of Virginia Health Sciences Center, Charlottesville

    For those who do not know offhand the meaning of acronyms such as FISH, SKY, CGH, etc., this book is a godsend that should be on the reference shelf of their medical libraries. For those who want to use it as a textbook, the editor and his associates have prepared a set of study questions. Professional cytogeneticists should have it handy for visitors or residents who are assigned to their laboratories for rotation. This is a truly multifunctional book that deserves to made available to a wide range of readers.
    - Modern Pathology

    Medical Cytogenetics...contains extensive color plates, black and white photographs, and other figures and tables....The excellent illustrations make this book even more valuable because information can be assimilated both visually and textually....
    ...of great value to anyone involved in the field...an excellent reference for all of the basic concepts of cytogenetics....the breadth of this book and attention to illustration and example make it stand out. The book also contains up-to-date reviews of many rapidly and expanding areas of knowledge...an excellent starting place for anyone interested in these topics and these chapters will serve as references in future years because of their clear descriptions of procedures and researching findings and excellent illustrations. The beautiful and illustrative color plates of FISH results deserve special mention. Medical Cytogenetics provides the reader with a comprehensive understanding of the field and sense of excitement about the future potential of this rapidly evolving science.
    - The Journal of the Association of Genetic Technologists, 2001