1st Edition

Medical Ethics, Prediction, and Prognosis Interdisciplinary Perspectives

204 Pages
by Routledge

204 Pages 20 B/W Illustrations
by Routledge

204 Pages 20 B/W Illustrations
by Routledge

Recent scientific developments, in particular advances in pharmacogenetics and molecular genetics, have given rise to numerous predictive procedures for detecting predispositions to diseases in patients. This knowledge, however, does not necessarily promise benign results for either patients or health care professionals. The aim of this volume is to analyse issues related to prediction and... Read more

Introduction: Predictive Medicine – An Interdisciplinary Approach

Mariacarla Gadebusch Bondio, Francesco Spöring, and John-Stewart Gordon

Part I. Individual Challenges

1. Beyond the Causes of Disease: Prediction and the Need for a New Philosophy of Medicine

Mariacarla Gadebusch Bondio

2. Comprehending and Communicating Statistics in Breast Cancer Screening. Ethical Implications and Potential Solutions

Giulia Ferretti, Alma Linkeviciute, and Giovanni Boniolo

3. On the Nature of the Right Not to Know

John-Stewart Gordon

4. Predictive Diagnostic Testing for Late-Onset Neurological Diseases in Asymptomatic Minors: ‘Do No Harm’ and the Value of Knowledge

Heiner Fangerau, Florian Braune, and Christian Lenk

5. Incidental Findings in Genetic Testing

Elke Holinski-Feder and Verena Steinke-Lange

Part II. Social Challenges

6. Risk and Solidarity within Individualized Medicine

Konrad Ott

7. Anticipatory Medicalization: Predisposition, Prediction, and Proto-Disease, Expanding Medicalized Conditions

Peter Conrad and Miranda Waggoner

8. Predicting the Cost of Diseases in Resource-Poor Countries

Steffen Flessa

9. Genetic Disorders in Chinese Patients and Their Families: A Call for Action on Predictive Medicine

Xian-Ning Zhang and Ji Zuo

Part III. Research Challenges

10. Personalized Antidepressant Prescription: A Historical Perspective on Risks and Opportunities

Francesco Spöring

11. Predicting, Preventing, and Treating Alzheimer’s Disease: Current State and Future Challenges

Stefan F. Lichtenthaler

12. Early Detection, Prediction, and Prognosis of Alzheimer’s Disease

Simone Lista, Francesco Garaci, Nicola Toschi, and Harald Hampel

13. Immunoscore, Circulating Tumor Cells and Human-Derived Organoids as Potential Predictive Tools in Personalized Cancer Medicine

Agnieszka Pastuła

Biography

Mariacarla Gadebusch Bondio is Professor in the Institute for History and Ethics of Medicine at Technical University of Munich, Germany

Francesco Spöring is Research Assistant in the Institute for History and Ethics of Medicine at Technical University of Munich, Germany

John-Stewart Gordon is Professor of Philosophy and Head of the Applied Ethics Research Group at Vytautas Magnus University, Lithuania