1st Edition
Medicinal Chemistry A Look at How Drugs Are Discovered
Medicinal Chemistry: A Look at How Drugs Are Discovered is written for those who are interested in learning how drugs are discovered. Compared to other books on the market, this text takes a different approach by presenting the subject on chemical reaction mechanism terms, which ideally makes the subject matter more interesting and easier to comprehend. The authors describe the drug discovery process, from advancing an initial lead to the approval process, and include drug discovery sources.
Additional features:
- Explains medicinal chemistry on chemical mechanism terms, allowing for a more interesting and easier to comprehend text
- Includes valuable insights toward the various pathways taken at pharmaceutical industries in drug discoveries
- Improved by including questions raised and suggestions made from students in the authors’ medicinal chemistry classes
This book will benefit both upper level undergraduates and graduates studying in the fields of medicinal chemistry and drug discovery, as well as scientists working in the pharmaceutical industry.
Biography
A. K. Ganguly
Born in India, Prof. A. K. Ganguly was educated partly in India and in England. He attended the Imperial College of Science and Technology, London, where he obtained his Ph.D. in chemistry in 1961 under the supervision of Sir Derek Barton, a Nobel Laureate in chemistry,
After finishing his studies at the Imperial College Prof. Ganguly returned back to India to work for Glaxo Laboratories and later with the Ciba Research Center in Bombay. He immigrated to the USA in 1967 and after a brief stay at the Research Institute of Medicine and Chemistry, Cambridge, Massachusetts he joined Schering Plough Research Institute, Kenilworth, New Jersey in 1968 as a Senior Scientist and where he advanced to the position of Senior Vice President of Chemical Research. He is associated with the discovery of Zetia, Posaconazole, Lonafarnib and Boceprevir. He is a coauthor of 222 papers and a coinventor of 88 patents. He has received several awards including the E.B. Hershberg award for important discoveries in Medicinal Chemistry from the American Chemical Society. After retiring from Schering-Plough, he joined Stevens Institute of Technology, Hoboken, NJ as a Distinguished Research Professor of Chemistry and presently he continues to consult in the drug discovery area.
Sesha Sridevi Alluri
Dr. Sesha Alluri received her M.Sc. degree in medicinal chemistry in India and after working as a Senior Chemist at the Dr. Redddy’s Laboratories for a few years she immigrated to the United States and joined Stevens Institute of Technology, Hoboken, New Jersey. She received a second M.S degree and Ph.D. from the institute under the supervision of Prof. A. K. Ganguly. Presently, she is working as a Lecturer in the department of Chemistry and Chemical Biology at the Stevens Institute. She teaches undergraduate and graduate chemistry courses, including medicinal chemistry and also supervises undergraduate students in organic synthesis research projects. She is the recipient of several awards including the ACS/WCC/Eli Lilly award in 2012.
'The quality of this book is excellent. Explanations of the medicinal chemistry of drugs and their mechanisms assist in creating a visual image of what is occurring at a microscopic level. The book is very easy to comprehend.'
- Shivani Rajendra Patel, MD Candidate, East Tennessee State University Quillen College of Medicine
