1st Edition

Membrane Shape and Biological Function

Edited By José Carlos Bozelli Jr, Richard M. Epand Copyright 2025
304 Pages 17 Color & 60 B/W Illustrations
by CRC Press

304 Pages 17 Color & 60 B/W Illustrations
by CRC Press

Membrane Shape and Biological Function is an important guide for anyone interested in the dynamic world of biological membranes. The book explores how membrane shape influences crucial biological processes and highlights its practical applications. It delves into the mechanics of lipid bilayers, their role in cellular processes, and computational methods for understanding membrane remodeling,... Read more

Preface

In Memoriam and Acknowledgement

Abbreviations

1. The Effect of Membrane Deformation on the Spatial Distribution of Lipids

David W. Allender and Michael Schick

2. Flexible Surface Model for Lipid-Protein Interactions

Steven D. E. Fried and Michael F. Brown

3. Non-Lamellar Phases of Membrane Lipids

John M. Seddon and Arwen I. I. Tyler

4. Lipid Shape Matters

James Jennings, Enrico F. Semeraro and Georg Pabst

5. Continuum Modeling of Lipid Bilayers for Curvature Generation in Cellular Processes

P. Rangamani

6. Lipid Membrane Remodeling by (Bio)Polymers and Nanoparticles: Mechanistic Insights From Multi-Scale Simulations

Sanjoy Paul, Sayantan Mondal, Zeke A. Piskulich, Taraknath Mandal and Qiang Cui

7. Bicontinuous Inverted Cubic Phases as Tools for Studying the Mechanism of Membrane-Remodeling Proteins

David P. Siegel

8. Recognition of Membrane Curvature by the Amphipathic Lipid Packing Sensor (ALPS) Motif

Antoine Reynaud, Romain Gautier and Bruno Antonny

9. The Bending Rigidity of the Red Blood Cell Cytoplasmic Membrane

Sebastian Himbert and Maikel C. Rheinstädter

10. Shape and Function of the Golgi Apparatus

Felix Campelo

11. Inositol Lipids Are Key to Shaping Membranes and to Define the Cellular Lipid Landscape

Tamas Balla, Yeun Ju Kim, Amrita Mandal, Gergo Gulyas, Yang Niu, Alejandro Alvarez-Prats and Joshua Pemberton

12. Shaping Membranes in Cell-Cell Fusion

Kamran Melikov and Leonid V. Chernomordik

13. Lipid Bilayers as Platforms for Understanding Biological Memory and the Development of Neuromorphic Computing

C. P. Collier, D. Bolmatov and J. Katsaras

Index

Biography

Drs. José Carlos Bozelli Jr and Richard M. Epand have contributed to advance our understanding of the active role of membrane shape in cellular functions. Their groundbreaking research, which revealed an elegant hierarchic coupling between membrane shape and lipid composition, has demonstrated the profound influence of membrane shape on molecular properties. This work, which is of utmost importance, lays the foundation for assembling this book and for further research in the field.