Metabolism of Brain Peptides: 1st Edition (Hardback) book cover

Metabolism of Brain Peptides

1st Edition

By Gerard O'Cuinn

CRC Press

272 pages

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Hardback: 9780849376658
pub: 1995-06-09
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Description

Metabolism of Brain Peptides discusses neuropeptide metabolism in light of recent research. It describes the processing mechanisms in the production of biologically active peptides. It details distribution of the variety of neuropeptides in the brain and comprehensively reviews the effects of these neuropeptides on behavioral and physiological functions. The book also examines termination mechanisms for the biological activities of neuropeptides in light of recent knowledge of their distribution, their receptors and their possible inactivation enzymes in various functional regions of the brain and at the blood-brain barrier.

Table of Contents

The Production of Biologically Active Peptides in Brain Tissues, J. Donlon, University College of Galway, Republic of Ireland

Specific Aspects of Peptide Proteins

Peptide Amidation

Biological Activity of Peptides in Brain Tissues, F. Roman, Institut de Recherche Jouveinal, France

Introduction

Neuropeptide Y

Calcitonin-gene Related Peptide

Cholecystokinin

Galanin

Neurotensin

Neuropeptide Receptor-Ion Channel Coupling in the Mammalian Brain, P. Boden, Parke-Davis Neuroscience Research Centre, Cambridge, England

Methodological Approaches

Neuropeptides and Ion Channels: Mechanistic Studies

Inactivation of Thyrotropin Releasing Hormone (TRH). The TRH-Degrading Enzyme as a Regulator and/or Terminator of TRH Signals, K. Bauer, Max-Planck-Institute for Experimental Endocrinology, Hannover, Germany

Characteristics of the TRH-Degrading Serum Enzyme and the membrane-Bound TRH-Degrading Enzyme

Cellular and Subcellular Localization

Purification and Cloning

Hormonal Regulation of the TRH-Degrading Enzymes

Intracellular Peptide Turnover: Properties and Physiological Significance of the Major Peptide Hydrolases of Brain Cystosol, S. Wilk, Mount Sinai School of Medicine, New York, New York

Endopeptidases

Oligopeptidases

Exopeptidases

Omega Peptidases

Subject Categories

BISAC Subject Codes/Headings:
MED005000
MEDICAL / Anatomy
SCI049000
SCIENCE / Life Sciences / Biology / Molecular Biology
SCI086000
SCIENCE / Life Sciences / General
SCI089000
SCIENCE / Life Sciences / Neuroscience