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Recently, the importance of metal ions to the vital functions of living organisms, hence, their health and well-being, has become increasingly apparent. As a result, the long-neglected field of "bioinorganic chemistry" is now developing at a rapid pace. The research centers on the synthesis, stability, formation, structure, and reactivity of biological metal ion-containing compounds of low and high molecular weight. The metabolism and transport of metal ions and their complexes are being studied, and new models for complicated natural structures and processes are being devised and tested. The focal point of our attention is the connection between the chemistry of metal ions and their role for life.
No doubt, we are only at the brink of this process. Thus, it is with the intention of linking coordination chemistry and biochemistry in their widest sense that the Metal Ions in Biological Systems series reflects the growing field of "bioinorganic chemistry". We hope, also, that this series will help to break down the barriers among the historically separate spheres of chemistry, biochemistry, biology, medicine, and physics, with the expectation that a good deal of future outstanding discoveries will be made in the interdisciplinary areas of science.
Should this series prove a stimulus for new activities in this fascinating "field", it would serve its purpose and would be a satisfactory result for the efforts spent by the authors.
Edited By Helmut Sigel, Roland Sigel
December 02, 2019
Volume 44, devoted solely to the vital research areas concerning the biogeochemistry of metals and their transport in the environment and availability to living systems, offers 9 timely and authoritative chapters on these fascinating topics by 19 internationally recognized experts....
By Helmut Sigel
October 07, 2019
"Highlights the availability of magnesium to organisms, its uptake and transport in microorganisms and plants as well as its role in health and disease of animals and humans including its toxicology."...
Edited By Astrid Sigel, Helmut Sigel
October 02, 2019
Volume 39: Molybdenum and Tungsten: Their Roles in Biological Processes is devoted soley to the vital research area on molybdenum and tungsten and their role in biology. It offers a comprehensive and timely account of this fascinating topic by 40 distinguished international authorities. Topics ...
Edited By Helmut Sigel, Roland Sigel
September 25, 2019
Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, ...
Edited By Astrid Sigel
March 26, 2004
Metal ions are currently used for such applications as diabetes, anti-inflammatory, rheumatoid arthritis, psychiatric, and anti-ulcer medications, using compounds of vanadium, copper and zinc, gold, lithium, and bismuth, respectively. This text explores these applications in addition to an ...
Edited By Helmut Sigel
March 26, 2004
Offering an authoritative and timely account by twenty-nine internationally recognized experts, Metal Ions in Biological Systems: Metal Complexes in Tumor Diagnosis and as Anticancer Agents is devoted solely to the vital research area concerning metal complexes in cancer diagnosis and therapy. In ...
Edited By Helmut Sigel
March 27, 2003
The Metal Ions in Biological Systems series is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of ...
Edited By Astrid Sigel
January 30, 2001
"Focuses on the vibrant area of probing enzymes or proteins by metal ions and small complexes. Offers a summary of the basic characteristics of the amide bond, emphasizing its proton and metal ion interactions, including a quantitative analysis of its hydrolysis and formation."...
Edited By Astrid Sigel, Helmut Sigel
March 10, 1999
Continues the tradition of excellence established in previous volumes in this acclaimed series. Volume 36 focuses on the vibrant research area concerning the interrelation between free radicals and metal ions and their resulting effects on life processes; it offers an authoritative and timely ...
Edited By Astrid Sigel, Helmut Sigel
February 29, 1996
"Volume 33 focuses on the vibrant research area of probing nucleic acids--the carriers of the genetic code--by metal ion complexes of small molecules providing an authoritative, timely account of this fascinating topic by over 50 distinguished experts."...
Edited By Astrid Sigel, Helmut Sigel
February 05, 1996
Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer ...
Edited By Helmut Sigel, Astrid Sigel
February 08, 1994
This volume is devoted solely to the research area of metalloenzymes involving amino acid-residue and related radicals. Topics covered include: general considerations; structure, function and engineering of peroxidases; and ribonucleotide reductase in mammalian systems....