Metals, Fertility, and Reproductive Toxicity: 1st Edition (Hardback) book cover

Metals, Fertility, and Reproductive Toxicity

1st Edition

Edited by Mari S. Golub

CRC Press

280 pages | 2 B/W Illus.

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Hardback: 9780415700405
pub: 2005-11-10
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Description

Environmental endocrine disruptors have been at the heart of discussions about chemicals and their effects on fertility, but the focus has been on organic compounds and the role of metals has been largely overlooked - until now. Taking an organ-system-based approach, Metals, Fertility, and Reproductive Toxicity examines the effects of metals found in the everyday environment on fertility rates in humans and animal populations.

This volume summarizes and evaluates the literature in the area of metal effects on fertility and reproduction in humans, laboratory animals, and wildlife. International experts have contributed chapters that explore how the ovary, testes, uterine system, and neuroendocrine system, among others, respond to metal exposure. Reviewing both current knowledge and cutting edge data, the chapters focus on either a particular metal or a particular population.

A massive amount of data on this subject has been generated, summarized, and reviewed over the years. While there are many books available on metals toxicity and on reproductive toxicity, no current book explores both in the same volume. Culling information from throughout the literature, Metals, Fertility, and Reproductive Toxicity supplies an in-depth look at the role of metals in endocrine disruption and the spectrum of mechanisms involving metals that can influence reproduction.

Table of Contents

Introduction, M.S. Golub

REPRODUCTIVE TOXICITY OF MERCURY, CADMIUM, AND ARSENIC, M.S. Golub

Introduction

Mercury

Cadmium

Arsenic

References

REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF ORGANOTIN COMPOUNDS, M. Ema and A. Hirose

Introduction

Effects on Aquatic Organisms

Effects on Experimental Animals

Conclusions

References

ADVERSE EFFECTS OF ALUMINUM, URANIUM, AND VANADIUM ON REPRODUCTION AND INTRAUTERINE DEVELOPMENT IN MAMMALS, J.L. Domingo

Aluminum

Uramium

Vanadium

Conclusions

References

INTRAUTERINE AND REPRODUCTIVE TOXICITY OF NUTRITIONALLY ESSENTIAL METALS, M.S. Golub

Introduction

Studies in Humans

Studies in Animals

References

LEAD EXPOSURE AND ITS EFFECTS ON THE REPRODUCTIVE SYSTEM, R.Z. Sokol, M.D., M.P.H.

Sources and Routes of Exposure

Absorption and Metabolism

Physiology of Reproduction

Effects of Lead on Male Reproduction

Effects of Lead on Female Reproduction

Summary

References

IMPACT OF METALS ON OVARIAN FUNCTION, P.B. Hoyer, Ph.D.

Introduction

Ovarian Physiology

Sites of Disruption of Ovarian Function

Consequences of Ovarian Toxicity

Metals: Ovarian Effects

Summary and Future Directions

References

EPIDEMIOLOGICAL AND OCCUPATIONAL STUDIES OF METALS IN MALE REPRODUCTIVE TOXICITY, W.A. Robbins, Ph.D.

Introduction

Methodological Considerations in Studies

of Human Male Reproduction and Metals

Specific Metals and Human Male Reproduction

Summary

References

USE OF METAL REPRODUCTIVE TOXICITY DATA IN SELECTING ECOLOGICAL TOXICITY VALUES FOR SMALL MAMMALS INHABITING HAZARDOUS WASTE SITES, M.J. Anderson, J.T. Yamamoto, and H. Waites

Introduction

Toxicity Reference Values

Example of TRV Derivation: Lead

Predicting Potential Ecological Risks of Lead

Conclusions

References

Index

Subject Categories

BISAC Subject Codes/Headings:
MED082000
MEDICAL / Reproductive Medicine & Technology
MED096000
MEDICAL / Toxicology
SCI026000
SCIENCE / Environmental Science