1st Edition

Metered Dose Inhaler Technology

Edited By Tol S. Purewal, David J.W. Grant Copyright 1997
    280 Pages
    by CRC Press

    Metered Dose Inhaler Technology explores the technologies of pressurized metered dose inhalation (MDI) delivery systems and provides practical, easy-to-use guidance to effective product formulation. With contributions from an international panel of authors, the book addresses the global phase-out of chloroflurocarbon chemicals (CFCs), the generation of propellant systems to replace them, and their associated new medications and therapies. Topics include the manufacture of metered dose inhalers, particle size analysis in inhalation therapy, development and testing, pharmcokinetics and metabolism of propellants, toxicology, and more.

    o Introduction to MDI, T. Purewal
    o Formulation of Metered Dose Inhalers, T. Purewal
    o The Manufacture of Metered Dose Inhalers, A. Wilkinson
    o Particle Size Analysis in Inhalation Therapy, C. Washington
    o Analytical Development and Testing, H. Cummings, A. Childers, &
    M. Riebe
    o Pharmacokinetics and Metabolism of Propellants, L. Harrison
    o Toxicology of Propellants, C. Leach


    Tol S. Purewal, David J.W. Grant