Methods for Genetic Risk Assessment: 1st Edition (Hardback) book cover

Methods for Genetic Risk Assessment

1st Edition

By David Brusick

CRC Press

272 pages

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Hardback: 9781566700399
pub: 1994-01-11
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Description

Genetic disease contributes to a major portion of our health care costs. While most of the human genetic burden is transmitted from generation to generation, environmental chemicals capable of reacting with germ cell DNA could produce new mutations, resulting in an even greater genetic liability for the next generation. The potential impact of environmental mutagens on the health and viability of other living things is important to consider as well.

Methods for Genetic Risk Assessment features contributions from international experts to provide a comprehensive review of the current status of genetic risk assessment. You'll learn about various methods and strategies for when and how to conduct genetic risk assessments on human populations. You will also learn about the potential effects of environmental genotoxins on nonhuman organisms. Topics considered include:

Table of Contents

Comparative Risk Assessment Associated with Exposure of Human and Nonhuman Biota to Genotoxic Agents and Ionizing Radiation (M.D. Waters, D.M. DeMarini, A. Richard, and M.D. Shelby). Methods for Exposure Assessment to Genotoxic Agents (D.W. Layton, T. McKone, J. Knezovich, and J.J. Wong). Methods for Dose and Effect Assessment (J. Favor, J. Filser, U.H. Ehling, E. Vogel, and A.A. van Zeeland). Risk Characterization Strategies for Genotoxic Agents (J. Lewtas, D.M. DeMarini, J. Favor, D.W. Layton, J.T. MacGregor, J. Ashby, P.H.M. Lohman, R.H. Haynes, and M.L. Mendelsohn). Monitoring Environmental Genotoxicants: A Report of the ICPEMC Working Group on Environmental Monitoring (J. MacGregor, J. Lewtas, G.G. Pesch, R. Jensen, L.D. Claxton, and W.R. Lower).

Subject Categories

BISAC Subject Codes/Headings:
MED096000
MEDICAL / Toxicology
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
TEC010000
TECHNOLOGY & ENGINEERING / Environmental / General