Methods in Aging Research: 1st Edition (Hardback) book cover

Methods in Aging Research

1st Edition

By Byung Pal Yu

CRC Press

720 pages | 16 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9780849331121
pub: 1998-06-29

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Gerontological research is currently of great interest due to ever-increasing longevity of human life spans. Created to provide researchers and scientists with the technical methods essential to their work, Methods in Aging Research is a practical bench-top guide for everyone who plans, designs, or conducts research in aging. It highlights experimental procedures that are key to the investigation of the biological aging phenomena.

Methods in Aging Research is a state-of-the-art reference that offers the most direct and clear cut descriptions available of methodological procedures used in aging research. Methods and protocols are critically evaluated and the advantages and disadvantages of each technique are explored. More than 70 expert contributors from around the world share their combined knowledge on a broad range of topics essential to everyone involved in cultivating and developing the gerontological research frontier.

Table of Contents

General Theoretical Approaches to Aging Research

Population Study of Mortality and Longevity with Gompertzian Analysis, J.R. Carey

Design of Cross-Sectional, Longitudinal, and Sequential Studies in Gerontology, D. Ingram

Mathematical and Computational Tools for Gerontological Research, T.M. Witten

Experimental In Vitro Models in Aging Research

Use of the Fibroblast Model, V.J. Cristofalo, M. Tresini, C. Volker, and M.K. Francis

Electrophysiological Assessment of Aged

Hippocampus In Vivo and In Vitro, G.M. Rose, K.L. Heman, G.K. Payapali, and D.A. Turner

Using Drosophilia in Experimental Aging Research, R. Arking and R.C. Woodruff

Experimentation with Nematodes, A.Z. Reznick and D. Gershon

Experimentation with Yeast Model, S. Kim, P.A. Kirchman, A. Benguria, and S.M. Jazwinski

Vertebrate Models in Aging Research

Long-Term Housing of Rodents Under Specific Pathogen-Free Barrier Conditions, R.W. Hart, S.M. Lewis, B. Leard, and A. Turturro

Choice of Rodent Model for Aging Research, E.J. Masoro

Aging Experiments Using Non-Human Primates, R. Colman and J.W. Keminitz

Methods of Assessing Aging Processes

Dietary Restriction, H.A. Bertrand, J.T. Herlihy, Y. Ikeno, and B.P. Yu

Study Design for Nutritional Assessments in the Elderly, H. Payette, Y. Guigoz, and B.J. Vellas

Exercise, L.L. Ji and M.T. Gore

Changes in Neurotransmitter Exocytosis: A Target for Regulation During Aging, H.Y. Wang, D.L. Snyder, J. Roberts, and E. Friedman

Pathological Analysis in Aging Research, G.B. Hubbard and Y. Ikeno

Molecular and Evolutionary Probes of Senescence Alterations

Transgenic Manipulation of the Mouse Genome, C.A. Walter

Telomeres and Replicative Senescence, R.C. Allsopp, S.S. Wang, N.W. Kim, and C. B.Harley

Evolutionary Approaches to Probing Aging Mechanisms, S.N. Austad and D.J. Holmes

Apoptosis and Programmed Cell Death, I.D. Bowen

Mitochondrial DNA Deletions, M.N. Gadaleta, A.M.S. Lezza, and P. Cantatore

Techniques for Exploring Age-Related Intra- and Subcellular Changes

Intracellular Signal Transduction Pathways Involved in Hepatocyte DNA Synthesis Following Growth Factor Stimulation, Y. Liu,, N.J. Holbrook, G.C. Kokkonen, S. Kitano, and G.S. Roth

Measurements of Mitochondrial Oxygen Radical Production, G. Barja

Methods for the Study of Immune Cells in Aging, G. Fernandes

Techniques for Assessing Age-Related Oxidative Modification

Techniques for Assessing Age-Related Oxidative Modification, M. Matsuo and T. Kaneko

Measurement of Oxidative DNA Damage Using the Technique of Gas Chromatography-Mass Spectrometry, M. Dizdaroglu

A Transgenic Mouse Model for Studying Mutations In Vivo, J. Vijg, M.E.T. Dolle, and M.E.T.I. Boerrigter

Protein Oxidation, P.E. Starke-Reed

Glycation, Glycoxidation, and Other Maillard Reaction Products, V.M. Monnier, J.F. Fogarty, and D.R. Sell

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Geriatrics
SCIENCE / Research & Methodology
SCIENCE / Life Sciences / Neuroscience