1st Edition

Micro- and Nanotechnologies-Based Product Development



  • Available for pre-order. Item will ship after September 7, 2021
ISBN 9780367488451
September 7, 2021 Forthcoming by CRC Press
352 Pages 50 Color & 13 B/W Illustrations

USD $200.00

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Book Description

This book provides comprehensive information of the nanotechnological based pharmaceutical product development including diverse range of arena liposome, nanoparticles, fullerenes, hydrogels, Thermally responsive externally activated theranostics (TREAT), hydrogel, microspheres, micro- and nanoemulsion, carbon nanomaterials and so on. We cover the micro- and nano-technological aspects for pharmaceutical product development with product development point of view and it covers the industrial aspects, novel technologies, stability studies, validation, safety and toxicity profiles, regulatory perspectives, scale up technologies and fundamental concept in development of product.

Salient Features:

  1. Covers micro- and Nano- technologies approaches with current trends with safety and efficacy in product development.
  2. Presents overview of recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements.
  3. Provides comprehensive overview of latest research related to the micro and nanotechnological including designing, optimization, validation, scale of micro and nanotechnologies.
  4. This book is edited by the two-well known researchers by contribution of the vivid chapters from renowned scientists across the globe in field of pharmaceutical sciences.

Table of Contents

Section A: Introduction

  1. Micro- and Nanotechnologies Approaches: Concepts and Application
  2. Bhavnana Valamla, Pradip Thakor, Arvind Gulbake, Satish Shilpi and Neelesh Kumar Mehra

  3. Formulation by Design: An Emerging Approach for Designing of Vesicular Nanocarriers
  4. Shiv Kumar Prajapati, Payal Kesharwani, Nishi Mody, Ashok M. Raichur, Swapnil Sharma,and Ankit Jain

  5. Thermally Responsive Externally Activated Theranostics (TREAT) for On-Demand Multifunctional Drug Delivery Systems
  6. Renuka Khatik, Akansha Jain, and Faheem Hyder Potto

  7. C60-fullerenes as an Emerging Cargo Carrier for the Delivery of Anti-neoplastic Agents: Promises and Challenges
  8. Nagarani Thotakura, and Kaisar Raza

    Section B: Bioactives Delivery System

  9. Pharmaceutical and Biomedical Application of Multifunctional Quantum dots
  10. Devesh Kapoor, Swapnil Sharma, Kanika Verma, Akansha Bisth, Yashu Chourasiya, Mayank Sharma, Anil Pethe and Rahul Maheshwari

  11. PLGA Based Micro- and Nano-particles: From Lab to Market
  12. Akash Chaurasiya, Parameswar Patra, Pranathi Thathireddy, and Amruta Gorajiya

  13. Targeted Stable Nucleic Acid Lipid Based Nanoparticles in Cancer Therapy
  14. Prashant Upadhaya, Swapnil Talkar, Vinod Ghodake, Namrata Kadwadkar, Anjali Pandya, Sreeranjini Pulakkat, and Vandana B. Patravale

  15. Ophthalmic Delivery of Hydrophilic Drugs: Nanotherapeutics and Reverse Micelle Based Formulation Strategies
  16. Arehalli Manjappa, Popat Kumbhar, Suraj Pattekari, John Disouza, and Vandana B. Patravale

  17. Metal Nanoparticles As a Surrogate Carrier in Drug Delivery and Diagnostics
  18. Sushama Talegaonkar, Surya Goel, Debopriya Dutta, Ruchi Singh, and Namita Chaudhary

  19. Resealed Erytherocytes: A biological carrier for drug delivery
  20. Satish Shilpi, Kapil Khatri, Umesh Dhakad, Neelesh Kumar Mehra, and Arvind Gulbake

  21. Nanostructured hydrogels-based biosensor platform
  22. Anand Singh Patel, and Keerti jain

  23. Multifunctional carbon nanotubes in Drug Delivery
  24. Anamika Sahu Gulbake, Ankit gaur, Aviral Jain, Neelesh Kumar Mehra, Satish Shilpi, and Arvind Gulbake

    Section C: Product Development, Toxicity and Scale-Up

  25. Liposomal based pharmaceutical Formulations-Current Landscape and Limitations and Technologies for Industrial Scale-up
  26. Radha Rani, Neha Raina, Azmi Khan, Manupriya Choudhary and Madhu Gupta

  27. Impact and Role of stability studies in parenteral product development
  28. Mohammed Asadullah Jahangir, Syed Sarim Imam, and Jayamanti Pandit

  29. Role of Reverse Engineering in Product Development
  30. Rishi Paliwal, Aanjaneya Mamgain, Rameshroo Kenwat, and Shivani Rai Paliwal

  31. Role of Polymers in Formulation Design and Drug Delivery
  32. Satish Shilpi, Umesh Dhakad, Rajkumari Lodhi, Sonal Dixit, Neelesh Kumar Mehra, Kapil Khatri

  33. Biodegradable Sterile Nanoparticles for the Treatment of Neurodegenerative Disease
  34. Iara Baldim, Adriana M. Ribeiro, João Dias-Ferreira, Wanderley P. Oliveira, Francisco M. Gama, and Eliana B. Souto

  35. Validation, Scale up and Technology Transfer in Product Development
  36. Arvind Gulbake, Ankit Gaur, Anamika Sahu, and Neelesh Kumar Mehra

  37. Nanotoxicology: Safety and Toxicity and Regulatory Consideration

Raja Susmitha, Mounika Gayathri Tirumala, Aslam Saifi and Chandraiah Godugu

References…………………………………………………………………………………

Index………………………………………………………………………………………..

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Editor(s)

Biography

Dr. Neelesh Kumar Mehra is working as an Assistant Professor of Pharmaceutics & Biopharmaceutics, at the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He earned his PhD from Dr. H.S. Gour University, Sagar and PostDoc from Irma Lerma Rangel College of Pharmacy, Texas A & M Health Science Centre, Kingsville, TX, USA. He served as Manager in Product Development, Sentiss Research Centre, Sentiss Pharma Pvt Ltd. Gurgaon for development, scale-up and technology transfer of complex ophthalmic, inhalation and optic pharmaceutical products. He received ‘TEAM AWARD’ for successful commercialisation of Ophthalmic Suspension product. He has authored more than 60 peer-reviewed publications in high repute International Journals, and >10 book chapter contributions. He has filed patent on manufacturing process and composition to improved therapeutic efficacy for topical delivery. He guided PhD and M.S. students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist and Team Awards for their research output. He is a peer reviewer of various international Journals and publishers. He recently published one edited book "Dendrimers in Nanomedicine Concept, Theory and Regulatory Perspectives" in CRC Press. Currently, he is editing books on Biopharmaceutical and nanotechnology based with Elsevier Pvt Ltd. He has rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nanotechnologies for regulated market and so on.

Dr. Arvind Gulbake is working as an Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical & Population Health Informatics at DIT University, Dehradun. Earlier, he was worked as a Coordinator, Research & Development, Centre for Interdisciplinary Research, D.Y. Patil Education Society, Institutions Deemed to be University, Kolhapur, Maharashtra, India. He earned his PhD with Prof. Sanjay K. Jain from Dr. Harisingh Gour University, Sagar. He has authored more than 40 peer-reviewed publications in high repute International Journals, 4 book chapters and a patent contribution. He guided PhD and M.S. students for their dissertations/research projects. He successfully completed extramural project funded by SERB, New Delhi, Government of India. He has received outstanding awards including Young Scientist and BRG Travel Award for his research. He is a peer reviewer of various International Journals and publishers. He is an assistant editor for International Journal of Applied Pharmaceutics and editorial board member in Journal of Liposome Research. He is a member of various academic committees at University level i.e., Board of Studies (Masters and Ph.D.), IBSC, IAEC, IQAC and Institutional Research Committee. He has more than 12 years of research and teaching experience in the formulation and development of nanopharmaceuticals