1st Edition

Microarray Innovations Technology and Experimentation

Edited By Gary Hardiman Copyright 2009
360 Pages
by CRC Press

360 Pages
by CRC Press

314 Pages
by CRC Press

In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation... Read more

Introduction to Gene Expression Profiling with DNA Microarray Technology. Introduction to Large-Scale Gene Expression Data Analysis. The Statistical Design and Analysis of Gene Expression Data. Laboratory Automation for Microarray Experimentation. How to Evaluate a Microarray Scanner. The Role of Substrates in Microarray Experimentation and How to Choose the Correct Coating for Microarraying. Towards Highly Efficient Automated Hybridizations. Characterization of Microarray Hybridization Stoichiometry. Data Normalization Selection. Methods for Assessing Microarray Performance. Comparison of Different Normalization Methods for Applied Biosystems Expression Array System. A Systematic Comparison of Gene Expression Measurements Across Different Hybridization-Based Technologies. DNA Methylation Arrays: Methods and Analysis. Electronic Microarrays: Progress toward DNA Diagnostics. New Applications for Microarrays. Development of an Oligonucleotide Microarray for Mutational Analysis Using Single or Multiple Sample Hybridization. Development of an Integrated Molecular Diagnostic Test to Identify Respiratory Viruses. Microarrays in Neuroscience. Optimization of Protein Array Fabrication for Establishing High Throughput Ultra-Sensitive Microarray Assays for Cancer Research. Index.





 

Biography

Gary Hardiman